New methods for the arylation of trivalent phosphorus species and Studies towards the synthesis of sesqui-lignan natural products
Chapter one describes two efficient synthesis methods for the preparation of functionalised phosphonium salts. The first method utilises aryl radicals generated by a photo-induced decomposition of diaryliodonium salts, with the second method generating aryl radicals from arylboronic acids and mangan...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2017
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| Online Access: | https://eprints.nottingham.ac.uk/42420/ |
| _version_ | 1848796483745218560 |
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| author | Fearnley, Adam |
| author_facet | Fearnley, Adam |
| author_sort | Fearnley, Adam |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Chapter one describes two efficient synthesis methods for the preparation of functionalised phosphonium salts. The first method utilises aryl radicals generated by a photo-induced decomposition of diaryliodonium salts, with the second method generating aryl radicals from arylboronic acids and manganese acetate. In both cases a broad substrate scope is demonstrated with respect to both the phosphorus and arylating species.
Chapter two describes approaches to the total synthesis of plant sesqui-neolignans. The synthesis of macranthol was achieved in 5 steps from commercially available 4-allylanisole in 7% yield. As well as the first synthesis of the core [4.3.0] ring structure of the fargenin/fargenone family of natural products. |
| first_indexed | 2025-11-14T19:48:42Z |
| format | Thesis (University of Nottingham only) |
| id | nottingham-42420 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T19:48:42Z |
| publishDate | 2017 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-424202025-02-28T13:45:19Z https://eprints.nottingham.ac.uk/42420/ New methods for the arylation of trivalent phosphorus species and Studies towards the synthesis of sesqui-lignan natural products Fearnley, Adam Chapter one describes two efficient synthesis methods for the preparation of functionalised phosphonium salts. The first method utilises aryl radicals generated by a photo-induced decomposition of diaryliodonium salts, with the second method generating aryl radicals from arylboronic acids and manganese acetate. In both cases a broad substrate scope is demonstrated with respect to both the phosphorus and arylating species. Chapter two describes approaches to the total synthesis of plant sesqui-neolignans. The synthesis of macranthol was achieved in 5 steps from commercially available 4-allylanisole in 7% yield. As well as the first synthesis of the core [4.3.0] ring structure of the fargenin/fargenone family of natural products. 2017-07-18 Thesis (University of Nottingham only) NonPeerReviewed application/pdf en arr https://eprints.nottingham.ac.uk/42420/1/Adam%20Fearnley%20Thesis.pdf Fearnley, Adam (2017) New methods for the arylation of trivalent phosphorus species and Studies towards the synthesis of sesqui-lignan natural products. PhD thesis, University of Nottingham. |
| spellingShingle | Fearnley, Adam New methods for the arylation of trivalent phosphorus species and Studies towards the synthesis of sesqui-lignan natural products |
| title | New methods for the arylation of trivalent phosphorus species
and Studies towards the synthesis of sesqui-lignan natural products |
| title_full | New methods for the arylation of trivalent phosphorus species
and Studies towards the synthesis of sesqui-lignan natural products |
| title_fullStr | New methods for the arylation of trivalent phosphorus species
and Studies towards the synthesis of sesqui-lignan natural products |
| title_full_unstemmed | New methods for the arylation of trivalent phosphorus species
and Studies towards the synthesis of sesqui-lignan natural products |
| title_short | New methods for the arylation of trivalent phosphorus species
and Studies towards the synthesis of sesqui-lignan natural products |
| title_sort | new methods for the arylation of trivalent phosphorus species
and studies towards the synthesis of sesqui-lignan natural products |
| url | https://eprints.nottingham.ac.uk/42420/ |