Effect of polymer topology on non-covalent polymer-protein complexation: miktoarm versus linear mPEG-poly(glutamic acid) copolymers

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Effect of polymer topology on non-covalent polymer-protein complexation: miktoarm versus linear mPEG-poly(glutamic acid) copolymers

Non-covalent polymer-protein conjugation is emerging as a potential route to improve pharmacokinetics and pharmacodynamics of protein therapeutics. In this study, a family of structurally related block copolymers of mPEG2k - poly(glutamic acid) with linear A-B (mPEG2k-lin-polyGA) and miktoarm A-B3 (...

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Bibliographic Details
Main Authors:	Nieto-Orellana, Alejandro, Di Antonio, Marco, Conte, Claudia, Falcone, Franco H., Bosquillon, Cynthia, Childerhouse, Nick, Mantovani, Giuseppe, Stolnik, Snow
Format:	Article
Published:	Royal Society of Chemistry 2017
Online Access:	https://eprints.nottingham.ac.uk/41847/

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