Investigation of the effect of insertional mutation in agr and sigB loci in Clostridium difficile R20291

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Investigation of the effect of insertional mutation in agr and sigB loci in Clostridium difficile R20291

Clostridium difficile has become the major cause of healthcare acquired diarrhoea in the world. The disease caused by this pathogen is largely mediated by the production of toxins. The C. difficile genome contains an incomplete accessory gene regulator (agr) locus, designated agr1. In Staphylococcus...

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Bibliographic Details
Main Author:	Montfort-Gardeazabal, Jorge M.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2017
Subjects:	C. difficile; Quorum Sensing; agr; sigB; ClosTron
Online Access:	https://eprints.nottingham.ac.uk/41809/

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