The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens
Campylobacter is the leading cause of foodborne diarrhoeal illness in humans and is mostly acquired from consumption or handling of contaminated poultry meat. In the absence of effective licensed vaccines and inhibitors, selection for chickens with increased resistance to Campylobacter could potenti...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Published: |
BIOMED
2016
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/41760/ |
| _version_ | 1848796348255567872 |
|---|---|
| author | Psifidi, A. Fife, M. Howell, J. Matika, O. van Diemen, P.M. Kuo, Richard Smith, J. Hockling, P.M. Salmon, N. Jones, M.A. Hume, D.A. Banos, G. Stevens, M.P. Kaiser, P. |
| author_facet | Psifidi, A. Fife, M. Howell, J. Matika, O. van Diemen, P.M. Kuo, Richard Smith, J. Hockling, P.M. Salmon, N. Jones, M.A. Hume, D.A. Banos, G. Stevens, M.P. Kaiser, P. |
| author_sort | Psifidi, A. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Campylobacter is the leading cause of foodborne diarrhoeal illness in humans and is mostly acquired from consumption or handling of contaminated poultry meat. In the absence of effective licensed vaccines and inhibitors, selection for chickens with increased resistance to Campylobacter could potentially reduce its subsequent entry into the food chain. Campylobacter intestinal colonisation levels are influenced by the host genetics of the chicken. In the present study, two chicken populations were used to investigate the genetic architecture of avian resistance to colonisation: (i) a back-cross of two White Leghorn derived inbred lines [(61 x N) x N] known to differ in resistance to Campylobacter colonisation and (ii) a 9th generation advanced intercross (61 x N) line. |
| first_indexed | 2025-11-14T19:46:33Z |
| format | Article |
| id | nottingham-41760 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:46:33Z |
| publishDate | 2016 |
| publisher | BIOMED |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-417602020-05-04T17:46:09Z https://eprints.nottingham.ac.uk/41760/ The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens Psifidi, A. Fife, M. Howell, J. Matika, O. van Diemen, P.M. Kuo, Richard Smith, J. Hockling, P.M. Salmon, N. Jones, M.A. Hume, D.A. Banos, G. Stevens, M.P. Kaiser, P. Campylobacter is the leading cause of foodborne diarrhoeal illness in humans and is mostly acquired from consumption or handling of contaminated poultry meat. In the absence of effective licensed vaccines and inhibitors, selection for chickens with increased resistance to Campylobacter could potentially reduce its subsequent entry into the food chain. Campylobacter intestinal colonisation levels are influenced by the host genetics of the chicken. In the present study, two chicken populations were used to investigate the genetic architecture of avian resistance to colonisation: (i) a back-cross of two White Leghorn derived inbred lines [(61 x N) x N] known to differ in resistance to Campylobacter colonisation and (ii) a 9th generation advanced intercross (61 x N) line. BIOMED 2016-04-18 Article PeerReviewed Psifidi, A., Fife, M., Howell, J., Matika, O., van Diemen, P.M., Kuo, Richard, Smith, J., Hockling, P.M., Salmon, N., Jones, M.A., Hume, D.A., Banos, G., Stevens, M.P. and Kaiser, P. (2016) The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens. BMC Genomics, 17 . 293/1-293/18. ISSN 1471-2164 Campylobacter Chicken Colonisation Genetics Resistance http://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-016-2612-7 doi:10.1186/s12864-016-2612-7 doi:10.1186/s12864-016-2612-7 |
| spellingShingle | Campylobacter Chicken Colonisation Genetics Resistance Psifidi, A. Fife, M. Howell, J. Matika, O. van Diemen, P.M. Kuo, Richard Smith, J. Hockling, P.M. Salmon, N. Jones, M.A. Hume, D.A. Banos, G. Stevens, M.P. Kaiser, P. The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens |
| title | The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens |
| title_full | The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens |
| title_fullStr | The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens |
| title_full_unstemmed | The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens |
| title_short | The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens |
| title_sort | genomic architecture of resistance to campylobacter jejuni intestinal colonisation in chickens |
| topic | Campylobacter Chicken Colonisation Genetics Resistance |
| url | https://eprints.nottingham.ac.uk/41760/ https://eprints.nottingham.ac.uk/41760/ https://eprints.nottingham.ac.uk/41760/ |