A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic
Under investigation are the structural properties of gum arabic, an industrially important biopolymer for use as a stabilizer or in drug delivery, using Analytical Ultracentrifugation—a well-established, matrix-free probe for macromolecular size and shape. These results are combined with chromatogra...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Published: |
Wiley
2016
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/41700/ |
| _version_ | 1848796334769831936 |
|---|---|
| author | Gillis, Richard B. Adams, Gary G. Alzahrani, Qushmua Harding, Stephen E. Allen Bush, C. |
| author_facet | Gillis, Richard B. Adams, Gary G. Alzahrani, Qushmua Harding, Stephen E. Allen Bush, C. |
| author_sort | Gillis, Richard B. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Under investigation are the structural properties of gum arabic, an industrially important biopolymer for use as a stabilizer or in drug delivery, using Analytical Ultracentrifugation—a well-established, matrix-free probe for macromolecular size and shape. These results are combined with chromatographically-coupled methods (multi-angle light scattering, differential press imbalance viscometry) to provide a global analysis of its structure in varying ionic strength conditions. This analysis indicates that gum Arabic may have a compact, elliptical structure in solution, the significance of which for biotechnological use is indicated. This modelling method can be applied to other biopolymers and synthetic polymers. |
| first_indexed | 2025-11-14T19:46:20Z |
| format | Article |
| id | nottingham-41700 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:46:20Z |
| publishDate | 2016 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-417002020-05-04T20:01:07Z https://eprints.nottingham.ac.uk/41700/ A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic Gillis, Richard B. Adams, Gary G. Alzahrani, Qushmua Harding, Stephen E. Allen Bush, C. Under investigation are the structural properties of gum arabic, an industrially important biopolymer for use as a stabilizer or in drug delivery, using Analytical Ultracentrifugation—a well-established, matrix-free probe for macromolecular size and shape. These results are combined with chromatographically-coupled methods (multi-angle light scattering, differential press imbalance viscometry) to provide a global analysis of its structure in varying ionic strength conditions. This analysis indicates that gum Arabic may have a compact, elliptical structure in solution, the significance of which for biotechnological use is indicated. This modelling method can be applied to other biopolymers and synthetic polymers. Wiley 2016-09 Article PeerReviewed Gillis, Richard B., Adams, Gary G., Alzahrani, Qushmua, Harding, Stephen E. and Allen Bush, C. (2016) A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic. Biopolymers, 105 (9). pp. 618-625. ISSN 1097-0282 acacia; AUC; characterization; conformation; gum arabic; hydrodynamic; sedimentation velocity; ultracentrifugation http://onlinelibrary.wiley.com/doi/10.1002/bip.22823/abstract doi:10.1002/bip.22823 doi:10.1002/bip.22823 |
| spellingShingle | acacia; AUC; characterization; conformation; gum arabic; hydrodynamic; sedimentation velocity; ultracentrifugation Gillis, Richard B. Adams, Gary G. Alzahrani, Qushmua Harding, Stephen E. Allen Bush, C. A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic |
| title | A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic |
| title_full | A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic |
| title_fullStr | A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic |
| title_full_unstemmed | A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic |
| title_short | A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic |
| title_sort | novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic |
| topic | acacia; AUC; characterization; conformation; gum arabic; hydrodynamic; sedimentation velocity; ultracentrifugation |
| url | https://eprints.nottingham.ac.uk/41700/ https://eprints.nottingham.ac.uk/41700/ https://eprints.nottingham.ac.uk/41700/ |