Translating lung function genome-wide association study (GWAS) findings: new insights for lung biology

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Translating lung function genome-wide association study (GWAS) findings: new insights for lung biology

Chronic respiratory diseases are a major cause of worldwide mortality and morbidity. Although hereditary severe deficiency of α1 antitrypsin (A1AD) has been established to cause emphysema, A1AD accounts for only ∼1% of Chronic Obstructive Pulmonary Disease (COPD) cases. Genome-wide association studi...

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Bibliographic Details
Main Authors:	Kheirallah, Alexander K., Miller, Suzanne, Hall, Ian P., Sayers, Ian
Format:	Article
Published:	Elsevier 2016
Subjects:	ChIP-seq; Chromatin biology; Chronic obstructive pulmonary disease; Genome editing; Genome-wide association studies; Human tissue; Lung function; RNAseq; Single nucleotide polymorphism; Transgenic mouse
Online Access:	https://eprints.nottingham.ac.uk/41682/

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