Studying the cellular origin of HSCs in the zebrafish embryo and the role of Gfi1 transcription factors in their formation

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Studying the cellular origin of HSCs in the zebrafish embryo and the role of Gfi1 transcription factors in their formation

In vertebrates, haematopoietic stem cells (HSCs) maintain the blood system throughout life. HSCs are believed to arise during embryogenesis from haemogenic endothelial cells (HECs) that undergo an endothelial-to-haematopoietic transition (EHT). Here, in order to trace the progeny of the embryonic EC...

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Bibliographic Details
Main Author:	Jalali, Maryam
Format:	Thesis (University of Nottingham only)
Language:	English English English English English English English English English
Published:	2017
Online Access:	https://eprints.nottingham.ac.uk/41675/

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