Ruminant prion disease detection and characterisation using protein misfolding cyclic amplification

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Ruminant prion disease detection and characterisation using protein misfolding cyclic amplification

Prion diseases or transmissible spongiform encephalopathies (TSE) are characterised by the accumulation of a misfolded conformer (PrPSc) of a host encoded protein (PrPC). The misfolding event that leads to the formation PrPSc can be replicated in the in vitro amplification technique, protein misfold...

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Bibliographic Details
Main Author:	O'Connor, Matthew
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2017
Online Access:	https://eprints.nottingham.ac.uk/41599/

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