Genomic insights into cardiomyopathies: a comparative cross-species review
n the global human population, the leading cause of non-communicable death is cardiovascular disease. It is predicted that by 2030, deaths attributable to cardiovascular disease will have risen to over 20 million per year. This review compares the cardiomyopathies in both human and non-human animals...
| Main Authors: | , , |
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| Format: | Article |
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MDPI
2017
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| Online Access: | https://eprints.nottingham.ac.uk/41474/ |
| _version_ | 1848796282186891264 |
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| author | Simpson, Siobhan Rutland, Paul Rutland, Catrin S. |
| author_facet | Simpson, Siobhan Rutland, Paul Rutland, Catrin S. |
| author_sort | Simpson, Siobhan |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | n the global human population, the leading cause of non-communicable death is cardiovascular disease. It is predicted that by 2030, deaths attributable to cardiovascular disease will have risen to over 20 million per year. This review compares the cardiomyopathies in both human and non-human animals and identifies the genetic associations for each disorder in each species/taxonomic group. Despite differences between species, advances in human medicine can be gained by utilising animal models of cardiac disease; likewise, gains can be made in animal medicine from human genomic insights. Advances could include undertaking regular clinical checks in individuals susceptible to cardiomyopathy, genetic testing prior to breeding, and careful administration of breeding programmes (in non-human animals), further development of treatment regimes, and drugs and diagnostic techniques |
| first_indexed | 2025-11-14T19:45:30Z |
| format | Article |
| id | nottingham-41474 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:45:30Z |
| publishDate | 2017 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-414742020-05-04T18:38:25Z https://eprints.nottingham.ac.uk/41474/ Genomic insights into cardiomyopathies: a comparative cross-species review Simpson, Siobhan Rutland, Paul Rutland, Catrin S. n the global human population, the leading cause of non-communicable death is cardiovascular disease. It is predicted that by 2030, deaths attributable to cardiovascular disease will have risen to over 20 million per year. This review compares the cardiomyopathies in both human and non-human animals and identifies the genetic associations for each disorder in each species/taxonomic group. Despite differences between species, advances in human medicine can be gained by utilising animal models of cardiac disease; likewise, gains can be made in animal medicine from human genomic insights. Advances could include undertaking regular clinical checks in individuals susceptible to cardiomyopathy, genetic testing prior to breeding, and careful administration of breeding programmes (in non-human animals), further development of treatment regimes, and drugs and diagnostic techniques MDPI 2017-03-21 Article PeerReviewed Simpson, Siobhan, Rutland, Paul and Rutland, Catrin S. (2017) Genomic insights into cardiomyopathies: a comparative cross-species review. Veterinary Sciences, 4 (1). 19/1-19/26. ISSN 2306-7381 http://www.mdpi.com/2306-7381/4/1/19 doi:10.3390/vetsci4010019 doi:10.3390/vetsci4010019 |
| spellingShingle | Simpson, Siobhan Rutland, Paul Rutland, Catrin S. Genomic insights into cardiomyopathies: a comparative cross-species review |
| title | Genomic insights into cardiomyopathies: a comparative cross-species review |
| title_full | Genomic insights into cardiomyopathies: a comparative cross-species review |
| title_fullStr | Genomic insights into cardiomyopathies: a comparative cross-species review |
| title_full_unstemmed | Genomic insights into cardiomyopathies: a comparative cross-species review |
| title_short | Genomic insights into cardiomyopathies: a comparative cross-species review |
| title_sort | genomic insights into cardiomyopathies: a comparative cross-species review |
| url | https://eprints.nottingham.ac.uk/41474/ https://eprints.nottingham.ac.uk/41474/ https://eprints.nottingham.ac.uk/41474/ |