Analysis of the Ccr4-Not deadenylase complex: a biochemical and computational approach

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Analysis of the Ccr4-Not deadenylase complex: a biochemical and computational approach

In eukaryotic cells, the degradation of the mRNA poly(A) tail (deadenylation) is a crucial step in the regulation of gene expression. The Ccr4-Not complex is the major deadenylase enzyme involved in the mRNA deadenylation. The complex is composed by two subunits with ribonuclease activity (Caf1 and...

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Bibliographic Details
Main Author:	Balacco, Dario Leonardo
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2017
Subjects:	eukaryotic cells deadenylation gene expression
Online Access:	https://eprints.nottingham.ac.uk/41408/

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