Identification of functional variants in the Alzheimer’s disease candidate gene ABCA7

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Identification of functional variants in the Alzheimer’s disease candidate gene ABCA7

Late onset Alzheimer’s disease (LOAD) is the commonest form of dementia, affecting approximately 850,000 patients in the UK alone, predicted to exceed one million by 2025. The cause of LOAD is complex, but several large Genome Wide Association Studies have highlighted 21 genetic loci associated with...

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Bibliographic Details
Main Author:	Clement, Naomi Susan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2017
Subjects:	Alzheimer's disease Genetics Genetic loci Pathogenic mutations
Online Access:	https://eprints.nottingham.ac.uk/41405/

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