Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD)

This study investigated the neurobiological basis of comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). We compared children with ASD, ADHD or ADHD+ASD and typically developing controls (CTRL) on behavioural and electrophysiological correlates of...

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Main Authors: Groom, Madeleine J., Kochhar, Puja, Hamilton, Antonia, Liddle, Elizabeth B., Simeou, Marina, Hollis, Chris
Format: Article
Published: Springer 2017
Subjects:
Online Access:https://eprints.nottingham.ac.uk/41229/
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author Groom, Madeleine J.
Kochhar, Puja
Hamilton, Antonia
Liddle, Elizabeth B.
Simeou, Marina
Hollis, Chris
author_facet Groom, Madeleine J.
Kochhar, Puja
Hamilton, Antonia
Liddle, Elizabeth B.
Simeou, Marina
Hollis, Chris
author_sort Groom, Madeleine J.
building Nottingham Research Data Repository
collection Online Access
description This study investigated the neurobiological basis of comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). We compared children with ASD, ADHD or ADHD+ASD and typically developing controls (CTRL) on behavioural and electrophysiological correlates of gaze cue and face processing. We measured effects of ASD, ADHD and their interaction on the EDAN, an ERP marker of orienting visual attention towards a spatially cued location and the N170, a right-hemisphere lateralised ERP linked to face processing. We identified atypical gaze cue and face processing in children with ASD and ADHD+ASD compared with the ADHD and CTRL groups. The findings indicate a neurobiological basis for the presence of comorbid ASD symptoms in ADHD. Further research using larger samples is needed.
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spelling nottingham-412292020-05-04T19:57:31Z https://eprints.nottingham.ac.uk/41229/ Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) Groom, Madeleine J. Kochhar, Puja Hamilton, Antonia Liddle, Elizabeth B. Simeou, Marina Hollis, Chris This study investigated the neurobiological basis of comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). We compared children with ASD, ADHD or ADHD+ASD and typically developing controls (CTRL) on behavioural and electrophysiological correlates of gaze cue and face processing. We measured effects of ASD, ADHD and their interaction on the EDAN, an ERP marker of orienting visual attention towards a spatially cued location and the N170, a right-hemisphere lateralised ERP linked to face processing. We identified atypical gaze cue and face processing in children with ASD and ADHD+ASD compared with the ADHD and CTRL groups. The findings indicate a neurobiological basis for the presence of comorbid ASD symptoms in ADHD. Further research using larger samples is needed. Springer 2017-05 Article PeerReviewed Groom, Madeleine J., Kochhar, Puja, Hamilton, Antonia, Liddle, Elizabeth B., Simeou, Marina and Hollis, Chris (2017) Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). Journal of Autism and Developmental Disorders, 47 (5). pp. 1496-1509. ISSN 1573-3432 ASD; ADHD; ERPs; Comorbidity; Gaze cueing; Face processing http://link.springer.com/article/10.1007%2Fs10803-017-3078-4 doi:10.1007/s10803-017-3078-4 doi:10.1007/s10803-017-3078-4
spellingShingle ASD; ADHD; ERPs; Comorbidity; Gaze cueing; Face processing
Groom, Madeleine J.
Kochhar, Puja
Hamilton, Antonia
Liddle, Elizabeth B.
Simeou, Marina
Hollis, Chris
Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD)
title Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD)
title_full Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD)
title_fullStr Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD)
title_full_unstemmed Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD)
title_short Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD)
title_sort atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (asd) and attention deficit/hyperactivity disorder (adhd)
topic ASD; ADHD; ERPs; Comorbidity; Gaze cueing; Face processing
url https://eprints.nottingham.ac.uk/41229/
https://eprints.nottingham.ac.uk/41229/
https://eprints.nottingham.ac.uk/41229/