A laboratory-scale annular continuous flow reactor for UV photochemistry using excimer lamps for discrete wavelength excitation and its use in a wavelength study of a photodecarboxlyative cyclisation
This paper describes a new annular reactor for continuous UV photochemistry, which uses easily interchangeable excimer lamps of different wavelengths. The reactor has narrow clearance to form thin films of material for efficient irradiation of molecules. Its use is demonstrated by investigating the...
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| Format: | Article |
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Royal Society of Chemistry
2016
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| Online Access: | https://eprints.nottingham.ac.uk/41184/ |
| _version_ | 1848796215965122560 |
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| author | DeLaney, Erica N. Lee, Darren S. Elliott, Luke D. Jin, Jing Booker-Milburn, Kevin Poliakoff, Martyn George, Michael W. |
| author_facet | DeLaney, Erica N. Lee, Darren S. Elliott, Luke D. Jin, Jing Booker-Milburn, Kevin Poliakoff, Martyn George, Michael W. |
| author_sort | DeLaney, Erica N. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | This paper describes a new annular reactor for continuous UV photochemistry, which uses easily interchangeable excimer lamps of different wavelengths. The reactor has narrow clearance to form thin films of material for efficient irradiation of molecules. Its use is demonstrated by investigating the effect of discrete wavelength lamps (222, 282 and 308 nm) on the reaction of potassium N-phthalimidobutanoate 1. The ability of the reactor to be integrated into multistep processes is illustrated by combining it with an Amberlyst scavenger and a solid acid catalyst, NbOPO4, to access a second product 3 that is obtained in a single telescoped process. The tricyclic scaffold in 3 is a motif found in several biologically active compounds and has possibilities as a synthon for new pharmaceutical products. |
| first_indexed | 2025-11-14T19:44:27Z |
| format | Article |
| id | nottingham-41184 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:44:27Z |
| publishDate | 2016 |
| publisher | Royal Society of Chemistry |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-411842020-05-04T18:20:09Z https://eprints.nottingham.ac.uk/41184/ A laboratory-scale annular continuous flow reactor for UV photochemistry using excimer lamps for discrete wavelength excitation and its use in a wavelength study of a photodecarboxlyative cyclisation DeLaney, Erica N. Lee, Darren S. Elliott, Luke D. Jin, Jing Booker-Milburn, Kevin Poliakoff, Martyn George, Michael W. This paper describes a new annular reactor for continuous UV photochemistry, which uses easily interchangeable excimer lamps of different wavelengths. The reactor has narrow clearance to form thin films of material for efficient irradiation of molecules. Its use is demonstrated by investigating the effect of discrete wavelength lamps (222, 282 and 308 nm) on the reaction of potassium N-phthalimidobutanoate 1. The ability of the reactor to be integrated into multistep processes is illustrated by combining it with an Amberlyst scavenger and a solid acid catalyst, NbOPO4, to access a second product 3 that is obtained in a single telescoped process. The tricyclic scaffold in 3 is a motif found in several biologically active compounds and has possibilities as a synthon for new pharmaceutical products. Royal Society of Chemistry 2016-11-23 Article PeerReviewed DeLaney, Erica N., Lee, Darren S., Elliott, Luke D., Jin, Jing, Booker-Milburn, Kevin, Poliakoff, Martyn and George, Michael W. (2016) A laboratory-scale annular continuous flow reactor for UV photochemistry using excimer lamps for discrete wavelength excitation and its use in a wavelength study of a photodecarboxlyative cyclisation. Green Chemistry, 6 (19). pp. 1431-1438. ISSN 1463-9262 http://pubs.rsc.org/en/content/articlelanding/2017/gc/c6gc02888h#!divAbstract doi:10.1039/C6GC02888H doi:10.1039/C6GC02888H |
| spellingShingle | DeLaney, Erica N. Lee, Darren S. Elliott, Luke D. Jin, Jing Booker-Milburn, Kevin Poliakoff, Martyn George, Michael W. A laboratory-scale annular continuous flow reactor for UV photochemistry using excimer lamps for discrete wavelength excitation and its use in a wavelength study of a photodecarboxlyative cyclisation |
| title | A laboratory-scale annular continuous flow reactor for UV photochemistry using excimer lamps for discrete wavelength excitation and its use in a wavelength study of a photodecarboxlyative cyclisation |
| title_full | A laboratory-scale annular continuous flow reactor for UV photochemistry using excimer lamps for discrete wavelength excitation and its use in a wavelength study of a photodecarboxlyative cyclisation |
| title_fullStr | A laboratory-scale annular continuous flow reactor for UV photochemistry using excimer lamps for discrete wavelength excitation and its use in a wavelength study of a photodecarboxlyative cyclisation |
| title_full_unstemmed | A laboratory-scale annular continuous flow reactor for UV photochemistry using excimer lamps for discrete wavelength excitation and its use in a wavelength study of a photodecarboxlyative cyclisation |
| title_short | A laboratory-scale annular continuous flow reactor for UV photochemistry using excimer lamps for discrete wavelength excitation and its use in a wavelength study of a photodecarboxlyative cyclisation |
| title_sort | laboratory-scale annular continuous flow reactor for uv photochemistry using excimer lamps for discrete wavelength excitation and its use in a wavelength study of a photodecarboxlyative cyclisation |
| url | https://eprints.nottingham.ac.uk/41184/ https://eprints.nottingham.ac.uk/41184/ https://eprints.nottingham.ac.uk/41184/ |