The role of indoleamine 2,3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs

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The role of indoleamine 2,3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs

A controlled inflammatory response is required for protection against infection, but persistent inflammation causes tissue damage. Dendritic cells (DCs) have a unique capacity to promote both inflammatory and anti-inflammatory processes. One key mechanism involved in DC-mediated immunosuppression is...

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Bibliographic Details
Main Authors:	Salazar, Fabián, Awuah, Dennis, Negm, Ola H., Shakib, Farouk, Ghaemmaghami, Amir M.
Format:	Article
Published:	Nature Publishing Group 2017
Subjects:	Immune tolerance Conventional dendritic cells NF-kappaB
Online Access:	https://eprints.nottingham.ac.uk/41156/

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