Image quality transfer and applications in diffusion MRI

This paper introduces a new computational imaging technique called image quality transfer (IQT). IQT uses machine learning to transfer the rich information available from one-off experimental medical imaging devices to the abundant but lower-quality data from routine acquisitions. The procedure uses...

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Main Authors: Alexander, Daniel C., Zikic, Darko, Ghosh, Aurobrata, Tanno, Ryutaro, Wottschel, Viktor, Zhang, Jiaying, Kaden, Enrico, Dyrby, Tim B., Sotiropoulos, Stamatios N., Zhang, Hui, Criminisi, Antonio
Format: Article
Published: Elsevier 2017
Online Access:https://eprints.nottingham.ac.uk/41123/
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author Alexander, Daniel C.
Zikic, Darko
Ghosh, Aurobrata
Tanno, Ryutaro
Wottschel, Viktor
Zhang, Jiaying
Kaden, Enrico
Dyrby, Tim B.
Sotiropoulos, Stamatios N.
Zhang, Hui
Criminisi, Antonio
author_facet Alexander, Daniel C.
Zikic, Darko
Ghosh, Aurobrata
Tanno, Ryutaro
Wottschel, Viktor
Zhang, Jiaying
Kaden, Enrico
Dyrby, Tim B.
Sotiropoulos, Stamatios N.
Zhang, Hui
Criminisi, Antonio
author_sort Alexander, Daniel C.
building Nottingham Research Data Repository
collection Online Access
description This paper introduces a new computational imaging technique called image quality transfer (IQT). IQT uses machine learning to transfer the rich information available from one-off experimental medical imaging devices to the abundant but lower-quality data from routine acquisitions. The procedure uses matched pairs to learn mappings from low-quality to corresponding high-quality images. Once learned, these mappings then augment unseen low quality images, for example by enhancing image resolution or information content. Here, we demonstrate IQT using a simple patch-regression implementation and the uniquely rich diffusion MRI data set from the human connectome project (HCP). Results highlight potential benefits of IQT in both brain connectivity mapping and microstructure imaging. In brain connectivity mapping, IQT reveals, from standard data sets, thin connection pathways that tractography normally requires specialised data to reconstruct. In microstructure imaging, IQT shows potential in estimating, from standard “single-shell” data (one non-zero b-value), maps of microstructural parameters that normally require specialised multi-shell data. Further experiments show strong generalisability, highlighting IQT's benefits even when the training set does not directly represent the application domain. The concept extends naturally to many other imaging modalities and reconstruction problems.
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institution University of Nottingham Malaysia Campus
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publishDate 2017
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spelling nottingham-411232020-05-04T18:45:49Z https://eprints.nottingham.ac.uk/41123/ Image quality transfer and applications in diffusion MRI Alexander, Daniel C. Zikic, Darko Ghosh, Aurobrata Tanno, Ryutaro Wottschel, Viktor Zhang, Jiaying Kaden, Enrico Dyrby, Tim B. Sotiropoulos, Stamatios N. Zhang, Hui Criminisi, Antonio This paper introduces a new computational imaging technique called image quality transfer (IQT). IQT uses machine learning to transfer the rich information available from one-off experimental medical imaging devices to the abundant but lower-quality data from routine acquisitions. The procedure uses matched pairs to learn mappings from low-quality to corresponding high-quality images. Once learned, these mappings then augment unseen low quality images, for example by enhancing image resolution or information content. Here, we demonstrate IQT using a simple patch-regression implementation and the uniquely rich diffusion MRI data set from the human connectome project (HCP). Results highlight potential benefits of IQT in both brain connectivity mapping and microstructure imaging. In brain connectivity mapping, IQT reveals, from standard data sets, thin connection pathways that tractography normally requires specialised data to reconstruct. In microstructure imaging, IQT shows potential in estimating, from standard “single-shell” data (one non-zero b-value), maps of microstructural parameters that normally require specialised multi-shell data. Further experiments show strong generalisability, highlighting IQT's benefits even when the training set does not directly represent the application domain. The concept extends naturally to many other imaging modalities and reconstruction problems. Elsevier 2017-05-15 Article PeerReviewed Alexander, Daniel C., Zikic, Darko, Ghosh, Aurobrata, Tanno, Ryutaro, Wottschel, Viktor, Zhang, Jiaying, Kaden, Enrico, Dyrby, Tim B., Sotiropoulos, Stamatios N., Zhang, Hui and Criminisi, Antonio (2017) Image quality transfer and applications in diffusion MRI. NeuroImage, 152 . pp. 283-298. ISSN 1095-9572 http://www.sciencedirect.com/science/article/pii/S1053811917302008 doi:10.1016/j.neuroimage.2017.02.089 doi:10.1016/j.neuroimage.2017.02.089
spellingShingle Alexander, Daniel C.
Zikic, Darko
Ghosh, Aurobrata
Tanno, Ryutaro
Wottschel, Viktor
Zhang, Jiaying
Kaden, Enrico
Dyrby, Tim B.
Sotiropoulos, Stamatios N.
Zhang, Hui
Criminisi, Antonio
Image quality transfer and applications in diffusion MRI
title Image quality transfer and applications in diffusion MRI
title_full Image quality transfer and applications in diffusion MRI
title_fullStr Image quality transfer and applications in diffusion MRI
title_full_unstemmed Image quality transfer and applications in diffusion MRI
title_short Image quality transfer and applications in diffusion MRI
title_sort image quality transfer and applications in diffusion mri
url https://eprints.nottingham.ac.uk/41123/
https://eprints.nottingham.ac.uk/41123/
https://eprints.nottingham.ac.uk/41123/