Macroscopic coherent structures in a stochastic neural network: from interface dynamics to coarse-grained bifurcation analysis

We study coarse pattern formation in a cellular automaton modelling a spatially-extended stochastic neural network. The model, originally proposed by Gong and Robinson (Phys Rev E 85(5):055,101(R), 2012), is known to support stationary and travelling bumps of localised activity. We pose the model on...

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Main Authors: Avitable, Daniele, Wedgwood, Kyle C. A.
Format: Article
Published: Springer 2017
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Online Access:https://eprints.nottingham.ac.uk/41032/
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author Avitable, Daniele
Wedgwood, Kyle C. A.
author_facet Avitable, Daniele
Wedgwood, Kyle C. A.
author_sort Avitable, Daniele
building Nottingham Research Data Repository
collection Online Access
description We study coarse pattern formation in a cellular automaton modelling a spatially-extended stochastic neural network. The model, originally proposed by Gong and Robinson (Phys Rev E 85(5):055,101(R), 2012), is known to support stationary and travelling bumps of localised activity. We pose the model on a ring and study the existence and stability of these patterns in various limits using a combination of analytical and numerical techniques. In a purely deterministic version of the model, posed on a continuum, we construct bumps and travelling waves analytically using standard interface methods from neural field theory. In a stochastic version with Heaviside firing rate, we construct approximate analytical probability mass functions associated with bumps and travelling waves. In the full stochastic model posed on a discrete lattice, where a coarse analytic description is unavailable, we compute patterns and their linear stability using equation-free methods. The lifting procedure used in the coarse time-stepper is informed by the analysis in the deterministic and stochastic limits. In all settings, we identify the synaptic profile as a mesoscopic variable, and the width of the corresponding activity set as a macroscopic variable. Stationary and travelling bumps have similar meso- and macroscopic profiles, but different microscopic structure, hence we propose lifting operators which use microscopic motifs to disambiguate them. We provide numerical evidence that waves are supported by a combination of high synaptic gain and long refractory times, while meandering bumps are elicited by short refractory times.
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spelling nottingham-410322020-05-04T18:27:53Z https://eprints.nottingham.ac.uk/41032/ Macroscopic coherent structures in a stochastic neural network: from interface dynamics to coarse-grained bifurcation analysis Avitable, Daniele Wedgwood, Kyle C. A. We study coarse pattern formation in a cellular automaton modelling a spatially-extended stochastic neural network. The model, originally proposed by Gong and Robinson (Phys Rev E 85(5):055,101(R), 2012), is known to support stationary and travelling bumps of localised activity. We pose the model on a ring and study the existence and stability of these patterns in various limits using a combination of analytical and numerical techniques. In a purely deterministic version of the model, posed on a continuum, we construct bumps and travelling waves analytically using standard interface methods from neural field theory. In a stochastic version with Heaviside firing rate, we construct approximate analytical probability mass functions associated with bumps and travelling waves. In the full stochastic model posed on a discrete lattice, where a coarse analytic description is unavailable, we compute patterns and their linear stability using equation-free methods. The lifting procedure used in the coarse time-stepper is informed by the analysis in the deterministic and stochastic limits. In all settings, we identify the synaptic profile as a mesoscopic variable, and the width of the corresponding activity set as a macroscopic variable. Stationary and travelling bumps have similar meso- and macroscopic profiles, but different microscopic structure, hence we propose lifting operators which use microscopic motifs to disambiguate them. We provide numerical evidence that waves are supported by a combination of high synaptic gain and long refractory times, while meandering bumps are elicited by short refractory times. Springer 2017-02-01 Article PeerReviewed Avitable, Daniele and Wedgwood, Kyle C. A. (2017) Macroscopic coherent structures in a stochastic neural network: from interface dynamics to coarse-grained bifurcation analysis. Journal of Mathematical Biology, 75 (4). pp. 885-928. ISSN 0303-6812 Multiple scale analysis ; Mathematical neuroscience ; Refractoriness ; Spatio-temporal patterns ; Equation-free modelling ; Markov chains http://link.springer.com/article/10.1007/s00285-016-1070-9 doi:10.1007/s00285-016-1070-9 doi:10.1007/s00285-016-1070-9
spellingShingle Multiple scale analysis ; Mathematical neuroscience ; Refractoriness ; Spatio-temporal patterns ; Equation-free modelling ; Markov chains
Avitable, Daniele
Wedgwood, Kyle C. A.
Macroscopic coherent structures in a stochastic neural network: from interface dynamics to coarse-grained bifurcation analysis
title Macroscopic coherent structures in a stochastic neural network: from interface dynamics to coarse-grained bifurcation analysis
title_full Macroscopic coherent structures in a stochastic neural network: from interface dynamics to coarse-grained bifurcation analysis
title_fullStr Macroscopic coherent structures in a stochastic neural network: from interface dynamics to coarse-grained bifurcation analysis
title_full_unstemmed Macroscopic coherent structures in a stochastic neural network: from interface dynamics to coarse-grained bifurcation analysis
title_short Macroscopic coherent structures in a stochastic neural network: from interface dynamics to coarse-grained bifurcation analysis
title_sort macroscopic coherent structures in a stochastic neural network: from interface dynamics to coarse-grained bifurcation analysis
topic Multiple scale analysis ; Mathematical neuroscience ; Refractoriness ; Spatio-temporal patterns ; Equation-free modelling ; Markov chains
url https://eprints.nottingham.ac.uk/41032/
https://eprints.nottingham.ac.uk/41032/
https://eprints.nottingham.ac.uk/41032/