Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor

Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor

Despite decades of research in the epidermal growth factor receptor (EGFR) signalling field, and many targeted anti-cancer drugs that have been tested clinically, the success rate for these agents in the clinic is low, particularly in terms of the improvement of overall survival. Intratumoral hetero...

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Bibliographic Details
Main Authors: Weitsman, Gregory, Mitchell, Nicholas J., Evans, Rachel, Cheung, Anthony, Kalber, Tammy L., Bofinger, Robin, Fruhwirth, Gilbert O., Keppler, Melanie, Wright, Zoe V. F., Barber, Paul R., Gordon, Peter, Koning, Tamra de, Wulaningsih, Wahyu, Sander, Kerstin, Vojnovic, Borivoj, Hailes, Helen C., Tabor, Alethea B., Ng, Tony
Format: Article
Published: Nature Publishing Group 2017
Online Access:https://eprints.nottingham.ac.uk/40932/

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