Role of ROCK isoforms in regulation of stiffness induced myofibroblast differentiation in lung fibrosis

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Role of ROCK isoforms in regulation of stiffness induced myofibroblast differentiation in lung fibrosis

Fibrosis is a major cause of progressive organ dysfunction in several chronic pulmonary diseases. Rho associated coiled-coil forming kinase (ROCK) has shown to be involved in myofibroblast differentiation driven by altered matrix stiffness in fibrotic state. There are two known ROCK isoforms in huma...

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Bibliographic Details
Main Authors:	Htwe, Su S., Cha, Byung H., Yue, Kan, Khademhosseini, Ali, Knox, Alan J., Ghaemmaghami, Amir M.
Format:	Article
Published:	American Thoracic Society 2017
Online Access:	https://eprints.nottingham.ac.uk/40910/

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