Abnormal clock gene expression and locomotor activity rhythms in two month-old female APPSwe/PS1dE9 mice

Abnormal clock gene expression and locomotor activity rhythms in two month-old female APPSwe/PS1dE9 mice

In addition to cognitive decline, Alzheimer’s disease (AD) is also characterized by agitation and disruptions in activity and sleep. These symptoms typically occur in the evening or at night and have been referred to as ‘sundowning’. These symptoms are especially difficult for carers and there are n...

Full description

Bibliographic Details
Main Authors: Oyegbami, Olaide, Collins, Hilary M., Pardon, Marie-Christine, Ebling, Francis J.P., Heery, David M., Moran, Paula M.
Format: Article
Published: Bentham Science Publishing 2017
Subjects:
Alzheimer’s Disease
circadian
clock genes
APPswe/PS1dE9 mice
Per1
Per2
Cry1
Cry2
Bmal
Rev-Erb
Rev- Erbβ
Online Access:https://eprints.nottingham.ac.uk/40820/

Similar Items

Similar Items