Anti-confocal assessment of middle ear inflammation
To improve the diagnostic prediction of recurrence of otitis media with effusion after surgery, an anti-confocal system combined with spectroscopic measurements is proposed to reject unwanted signals from the eardrum and assess the blood content. The anti-confocal system was experimentally evaluated...
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| Format: | Article |
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Optical Society of America
2016
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| Online Access: | https://eprints.nottingham.ac.uk/40578/ |
| _version_ | 1848796090888880128 |
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| author | Jung, David S. Crowe, John A. Birchall, John P. Somekh, Michael G. See, Chung W. |
| author_facet | Jung, David S. Crowe, John A. Birchall, John P. Somekh, Michael G. See, Chung W. |
| author_sort | Jung, David S. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | To improve the diagnostic prediction of recurrence of otitis media with effusion after surgery, an anti-confocal system combined with spectroscopic measurements is proposed to reject unwanted signals from the eardrum and assess the blood content. The anti-confocal system was experimentally evaluated on both optical middle ear phantom and human skin. Results showed effective rejection of signals from the eardrum using a central stop replacing the confocal pinhole, while still detecting signals from the middle ear mucosa. The system is sensitive to changes in blood content, but scattering and absorption characteristics of the eardrum can distort the measurement. Confocal detection of eardrum properties was shown to be a promising approach to correct measurements. |
| first_indexed | 2025-11-14T19:42:28Z |
| format | Article |
| id | nottingham-40578 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:42:28Z |
| publishDate | 2016 |
| publisher | Optical Society of America |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-405782020-05-04T18:26:29Z https://eprints.nottingham.ac.uk/40578/ Anti-confocal assessment of middle ear inflammation Jung, David S. Crowe, John A. Birchall, John P. Somekh, Michael G. See, Chung W. To improve the diagnostic prediction of recurrence of otitis media with effusion after surgery, an anti-confocal system combined with spectroscopic measurements is proposed to reject unwanted signals from the eardrum and assess the blood content. The anti-confocal system was experimentally evaluated on both optical middle ear phantom and human skin. Results showed effective rejection of signals from the eardrum using a central stop replacing the confocal pinhole, while still detecting signals from the middle ear mucosa. The system is sensitive to changes in blood content, but scattering and absorption characteristics of the eardrum can distort the measurement. Confocal detection of eardrum properties was shown to be a promising approach to correct measurements. Optical Society of America 2016-12-12 Article PeerReviewed Jung, David S., Crowe, John A., Birchall, John P., Somekh, Michael G. and See, Chung W. (2016) Anti-confocal assessment of middle ear inflammation. Biomedical Optics Express, 8 (1). pp. 230-242. ISSN 2156-7085 Confocal microscopy Medical and biological imaging Otolaryngology Imaging through turbid media http://dx.doi.org/10.1364/BOE.8.000230 doi:10.1364/BOE.8.000230 doi:10.1364/BOE.8.000230 |
| spellingShingle | Confocal microscopy Medical and biological imaging Otolaryngology Imaging through turbid media Jung, David S. Crowe, John A. Birchall, John P. Somekh, Michael G. See, Chung W. Anti-confocal assessment of middle ear inflammation |
| title | Anti-confocal assessment of middle ear inflammation |
| title_full | Anti-confocal assessment of middle ear inflammation |
| title_fullStr | Anti-confocal assessment of middle ear inflammation |
| title_full_unstemmed | Anti-confocal assessment of middle ear inflammation |
| title_short | Anti-confocal assessment of middle ear inflammation |
| title_sort | anti-confocal assessment of middle ear inflammation |
| topic | Confocal microscopy Medical and biological imaging Otolaryngology Imaging through turbid media |
| url | https://eprints.nottingham.ac.uk/40578/ https://eprints.nottingham.ac.uk/40578/ https://eprints.nottingham.ac.uk/40578/ |