Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPARγ) are disrupted by retinal disease-associated mutations

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Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPARγ) are disrupted by retinal disease-associated mutations

Photoreceptor-specific nuclear receptor (PNR/NR2E3) and Tailless homolog (TLX/NR2E1) are human orthologs of the NR2E group, a subgroup of phylogenetically related members of the Nuclear Receptor (NR) superfamily of transcription factors. We assessed the ability of these NRs to form heterodimers with...

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Bibliographic Details
Main Authors:	Fulton, Joel, Mazumder, Bismoy, Whitchurch, Jonathan, Monteiro, Cintia J., Collins, Hilary M., Chan, Chun M., Clemente, Maria P., Hernandez Quiles, Miguel, Stewart, Elizabeth A., Amoaku, Winfried, Moran, Paula M., Mongan, Nigel P., Persson, Jenny L., Ali, Simak, Heery, David M.
Format:	Article
Published:	Nature Publishing Group 2017
Subjects:	nuclear receptor NR2E3 NR2E1 NR1C3 photoreceptor specific nuclear receptor (PNR) Tailless (TLX) peroxisome proliferator activated receptor (PPAR) dimerization protein protein interaction enhanced S-cone syndrome
Online Access:	https://eprints.nottingham.ac.uk/40567/

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