The Nottingham Fatigue After Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression
Objective: To identify factors associated with post-stroke fatigue in a sample of stroke survivors without depression. Design: Cross-sectional cohort study. Setting: Recruitment was from four stroke units in the UK. Subjects: Participants were assessed within four weeks of first stroke; those wi...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
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SAGE
2017
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| Online Access: | https://eprints.nottingham.ac.uk/40554/ |
| _version_ | 1848796084751564800 |
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| author | Drummond, Avril E.R. Hawkins, Loiuse Sprigg, Nikola Ward, Nick S. Mistri, Amit Tyrrell, Pippa Mead, Gillian E. Worthington, Esme Lincoln, Nadina |
| author_facet | Drummond, Avril E.R. Hawkins, Loiuse Sprigg, Nikola Ward, Nick S. Mistri, Amit Tyrrell, Pippa Mead, Gillian E. Worthington, Esme Lincoln, Nadina |
| author_sort | Drummond, Avril E.R. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Objective: To identify factors associated with post-stroke fatigue in a sample of stroke survivors without depression.
Design: Cross-sectional cohort study.
Setting: Recruitment was from four stroke units in the UK.
Subjects: Participants were assessed within four weeks of first stroke; those with high levels of depressive symptoms (score ≥7 Brief Assessment Schedule Depression Cards) were excluded.
Main measures: Participants were assessed four to six weeks after stroke on the Fatigue Severity Subscale of the Fatigue Assessment Inventory, the Rivermead Mobility Index, Nottingham Extended Activities of Daily Living scale, Beck Anxiety Index, Sleep Hygiene Index, 6m walk test, and measures of cognitive ability.
Results: Of the 371 participants recruited, 103 were excluded and 268 were assessed. Of the latter, the mean age was 67.7 years (SD 13.5) and 168 (63%) were men. The National Institutes of Health Stroke Scale mean score was 4.96 (SD 4.12). Post-stroke fatigue was reported by 115 (43%) of participants, with 71 (62%) reporting this to be a new symptom since their stroke. Multivariate analysis using the Fatigue Severity Scale as the outcome variable found pre-stroke fatigue, having a spouse/partner, lower Rivermead Mobility Index score, and higher scores on both the Brief Assessment Schedule Depression Cards and Beck Anxiety Index were independently associated with post-stroke fatigue, accounting for approximately 47% of the variance in Fatigue Severity Scale scores.
Conclusions: Pre-stroke fatigue, lower mood, and poorer mobility were associated with post-stroke fatigue. |
| first_indexed | 2025-11-14T19:42:22Z |
| format | Article |
| id | nottingham-40554 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:42:22Z |
| publishDate | 2017 |
| publisher | SAGE |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-405542020-05-04T18:32:19Z https://eprints.nottingham.ac.uk/40554/ The Nottingham Fatigue After Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression Drummond, Avril E.R. Hawkins, Loiuse Sprigg, Nikola Ward, Nick S. Mistri, Amit Tyrrell, Pippa Mead, Gillian E. Worthington, Esme Lincoln, Nadina Objective: To identify factors associated with post-stroke fatigue in a sample of stroke survivors without depression. Design: Cross-sectional cohort study. Setting: Recruitment was from four stroke units in the UK. Subjects: Participants were assessed within four weeks of first stroke; those with high levels of depressive symptoms (score ≥7 Brief Assessment Schedule Depression Cards) were excluded. Main measures: Participants were assessed four to six weeks after stroke on the Fatigue Severity Subscale of the Fatigue Assessment Inventory, the Rivermead Mobility Index, Nottingham Extended Activities of Daily Living scale, Beck Anxiety Index, Sleep Hygiene Index, 6m walk test, and measures of cognitive ability. Results: Of the 371 participants recruited, 103 were excluded and 268 were assessed. Of the latter, the mean age was 67.7 years (SD 13.5) and 168 (63%) were men. The National Institutes of Health Stroke Scale mean score was 4.96 (SD 4.12). Post-stroke fatigue was reported by 115 (43%) of participants, with 71 (62%) reporting this to be a new symptom since their stroke. Multivariate analysis using the Fatigue Severity Scale as the outcome variable found pre-stroke fatigue, having a spouse/partner, lower Rivermead Mobility Index score, and higher scores on both the Brief Assessment Schedule Depression Cards and Beck Anxiety Index were independently associated with post-stroke fatigue, accounting for approximately 47% of the variance in Fatigue Severity Scale scores. Conclusions: Pre-stroke fatigue, lower mood, and poorer mobility were associated with post-stroke fatigue. SAGE 2017-03-01 Article PeerReviewed Drummond, Avril E.R., Hawkins, Loiuse, Sprigg, Nikola, Ward, Nick S., Mistri, Amit, Tyrrell, Pippa, Mead, Gillian E., Worthington, Esme and Lincoln, Nadina (2017) The Nottingham Fatigue After Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression. Clinical Rehabilitation . ISSN 1477-0873 Stroke fatigue correlation depression mood http://journals.sagepub.com/action/doSearch?SeriesKey=crea&AllField=NotFast+study doi:10.1177/0269215517695857 doi:10.1177/0269215517695857 |
| spellingShingle | Stroke fatigue correlation depression mood Drummond, Avril E.R. Hawkins, Loiuse Sprigg, Nikola Ward, Nick S. Mistri, Amit Tyrrell, Pippa Mead, Gillian E. Worthington, Esme Lincoln, Nadina The Nottingham Fatigue After Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression |
| title | The Nottingham Fatigue After Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression |
| title_full | The Nottingham Fatigue After Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression |
| title_fullStr | The Nottingham Fatigue After Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression |
| title_full_unstemmed | The Nottingham Fatigue After Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression |
| title_short | The Nottingham Fatigue After Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression |
| title_sort | nottingham fatigue after stroke (notfast) study: factors associated with severity of fatigue in stroke patients without depression |
| topic | Stroke fatigue correlation depression mood |
| url | https://eprints.nottingham.ac.uk/40554/ https://eprints.nottingham.ac.uk/40554/ https://eprints.nottingham.ac.uk/40554/ |