The antimalarial drug primaquine targets Fe–S cluster proteins and yeast respiratory growth

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The antimalarial drug primaquine targets Fe–S cluster proteins and yeast respiratory growth

Malaria is a major health burden in tropical and subtropical countries. The antimalarial drug primaquine is extremely useful for killing the transmissible gametocyte forms of Plasmodium falciparum and the hepatic quiescent forms of P. vivax. Yet its mechanism of action is still poorly understood. In...

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Bibliographic Details
Main Authors:	Lalève, Anaïs, Vallieres, Cindy, Golinelli-Cohen, Marie-Pierre, Bouton, Cécile, Song, Zehua, Pawlik, Grzegorz, Tindall, Sarah M., Avery, Simon V., Clain, Jérôme, Meunier, Brigitte
Format:	Article
Published:	Elsevier 2016
Subjects:	Mitochondria; Malaria; Aconitase; Sod2; Oxidative stress; Yeast model; Primaquine
Online Access:	https://eprints.nottingham.ac.uk/40346/

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