Copy number variation of human AMY1 is a minor contributor to variation in salivary amylase expression and activity

QR Code

Copy number variation of human AMY1 is a minor contributor to variation in salivary amylase expression and activity

Background Salivary amylase in humans is encoded by the copy variable gene AMY1 in the amylase gene cluster on chromosome 1. Although the role of salivary amylase is well established, the consequences of the copy number variation (CNV) at AMY1 on salivary amylase protein production are less well...

Full description

Bibliographic Details
Main Authors:	Carpenter, Danielle, Mitchell, Laura, Armour, John A.L.
Format:	Article
Published:	BioMed Central 2017
Subjects:	Genome instability Amylase CNV Gene expression
Online Access:	https://eprints.nottingham.ac.uk/40334/

Similar Items

Recurrent rearrangements of human amylase genes create multiple independent CNV series
by: Shwan, Nzar A.A., et al.
Published: (2017)

Characterising amylase gene CNVs and application to association studies
by: Shwan, Nzar Ali Ameen
Published: (2018)

Obesity, starch digestion and amylase: association between copy number variants at human salivary (AMY1) and pancreatic (AMY2) amylase genes
by: Carpenter, Danielle, et al.
Published: (2015)

Measuring human salivary amylase copy number variation
by: Dhar, Sugandha
Published: (2010)

Extraction, purification and characterization of amylase enzyme from white pitaya (Hylocereus undatus (Haworth) britton & rose) peel using aqueous two- phase system
by: Shad, Zahra
Published: (2015)

Production and Characterization of Thermostable Amylases from Bacillus Circulans Isolated from a Local Hot Spring
by: Syed Aliee, Sharifah Srahrul Rabiah
Published: (1992)

Expression of recombinant geobacillus SP a-amylase in pichia pastoris GS 115
by: Gandhi, Sivasangkary
Published: (2014)

Molecular Cloning and Expression of a Thermostable Α-Amylase from Geobacillus Sp.
by: Kassaye, Elias Kebede
Published: (2009)

Inferring mechanisms of copy number change from haplotype structures at the human DEFA1A3 locus
by: Black, Holly A., et al.
Published: (2014)

Genome-wide methylation analysis identifies genes silenced in non-seminoma cell lines
by: Noor, Dzul Azri Mohamed, et al.
Published: (2016)

Flavour-saliva interactions: implications of submaxillary mucin and α-amylase
by: Dinu, Vlad
Published: (2020)

Intracellular Proteinase a Activities and Gene Expression of Isolated Candida Species in Malaysian and Iranian Patients
by: Saroukolaei, Shahla Amri
Published: (2011)

OmicsVolcano: Software for intuitive visualization and interactive exploration of high-throughput biological data
by: Kuznetsova, I., et al.
Published: (2021)

Suboptimal evolutionary novel environments promote singular altered gravity responses of transcriptome during Drosophila metamorphosis
by: Herranz, Raul, et al.
Published: (2013)

DNA content analysis of colorectal cancer defines a distinct ‘microsatellite and chromosome stable’ group but does not predict response to radiotherapy
by: Fadhil, Wakkas, et al.
Published: (2014)

Integrative analysis of copy number and gene expression in breast cancer using formalin-fixed paraffin-embedded core biopsy tissue: a feasibility study
by: Iddawela, Mahesh, et al.
Published: (2017)

Identification of candidate genes expressions and polymorphisms associated with atherosclerosis from postmortem cases in Hospital Kuala Lumpur and Hospital Serdang, Malaysia
by: Blin, Joan
Published: (2013)

Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity
by: Schurink, Anouk, et al.
Published: (2018)

Positional information resolves structural variations and uncovers an evolutionarily divergent genetic locus in accessions of Arabidopsis thaliana.
by: Lai, A., et al.
Published: (2011)

Extracellular enzyme production of Probiotic Bacillus JAQ04 and Micrococcus JAQ07 isolated from tiger grouper (Epinephelus fuscoguttatus)
by: M. Z., Nora Azirah, et al.
Published: (2016)

Cloning and Expression of Staphylococcus Epidermidis AT2 Lipase in Yarrowia Lipolytica
by: Mohd Nooh, Hisham
Published: (2011)

Gene expression, characterization and in silico studies of delta fatty acid desaturases
by: Abd Halim, Nur Farah Anis
Published: (2022)

Identification of suitable biomarkers for leptospiral molecular diagnosis and gene expression in Cavia porcellus linnaeus model
by: Kumaran, Sharmilah Kumari
Published: (2021)

The Ability of Nutrition to Mitigate Epigenetic Drift: A Novel Look at Regulating Gene Expression.
by: D Palmer, Raymond, et al.
Published: (2021)

From sequence to function: insights from natural variation in budding yeasts
by: Nieduszynski, Conrad A., et al.
Published: (2011)

Measuring the immune system of the three-spined stickleback: investigating natural variation by quantifying immune expression in the laboratory and the wild
by: Robertson, Shaun, et al.
Published: (2016)

Expression alterations define unique molecular characteristics of spinal ependymomas
by: Lourdusamy, Anbarasu, et al.
Published: (2015)

Analysis of the Ccr4-Not deadenylase complex: a biochemical and computational approach
by: Balacco, Dario Leonardo
Published: (2017)

Expression profile and function of Wnt signaling mechanisms in malignant mesothelioma cells
by: Fox, Simon, et al.
Published: (2013)

A molecular signature of dormancy in CD34+CD38- acute myeloid leukaemia cells
by: Al-Asadi, Mazin Gh., et al.
Published: (2017)

Characterization of MSP1 Promoter and Identification of Transcription Factors Involved in Regulation of Abscisic Acid- and Ethylene-Responsive Gene Expression in Oil Palm
by: Omidvar, Vahid
Published: (2011)

Characterisation and pathogenicity of Neofusicoccum ribis and gene expression study of pathogenesis-related genes in rubber (Hevea brasiliensis Muell. Arg)
by: Nyaka Ngobisa, Aurelie Irene Claire
Published: (2014)

Heterologous expression and characterization of L-asparaginase from marine Photobacterium sp. strain J15
by: Yaacob, Mohd Adilin
Published: (2014)

Rumen fermentation, fatty acid profiles, meat quality and adipogenesis related gene expression of goat and sheep fed with high concentrated diet
by: Su, Candyrine Chui Len
Published: (2016)

Isolation and gene expression profiling of drought-responsive genes in upland rice (Oryza sativa L.)
by: Lum, Mok Sam
Published: (2016)

Heterologous expression and secretion of Bacillus coagulans ST-6 xylanase in Lactococcus lactis NZ9000
by: Roslan, Abdullah Munir
Published: (2017)

Metabolite profiling, lignin accumulation and gene expression of oil palm germinated seed treated with Hendersonia GanoEF1
by: Ismail, Muhammad Faiz
Published: (2019)

Transcriptomic analysis of barley plant responses to cold stress
by: Wu, Jing
Published: (2010)

Investigating association of predisposition genes as a risk of developing multifactorial diseases
by: Arginbekova, Assel
Published: (2023)

Comprehensive annotation of the Parastagonospora nodorum reference genome using next-generation genomics, transcriptomics and proteogenomics
by: Syme, Robert, et al.
Published: (2016)