Influence of acid-base imbalance and hyperlipidaemia on statin-induced myotoxicity

QR Code

Influence of acid-base imbalance and hyperlipidaemia on statin-induced myotoxicity

Disturbances in the acid-base balance, such as acidosis and alkalosis, alone or in the presence of postprandial or pathological hyperlipidaemia can alter the pharmacological and toxicological outcomes of statin therapy. Both acid-base imbalance and hyperlipidaemia are quite common among statin users...

Full description

Bibliographic Details
Main Author:	Taha, Dhiaa A.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2017
Subjects:	Acidosis alkalosis Chylomicrons Hyperlipidemia Lipoproteins Myotoxicity Simvastatin Pravastatin
Online Access:	https://eprints.nottingham.ac.uk/40222/

Similar Items

Hyperlipidaemia alone and in combination with acidosis can increase the incidence and severity of statin-induced myotoxicity
by: Taha, Dhiaa A., et al.
Published: (2017)

The role of acid-base imbalance in statin-induced myotoxicity
by: Taha, Dhiaa A., et al.
Published: (2016)

Lipophilicity predicts the ability of nonsulphonylurea drugs to block pancreatic beta-cell KATP channels and stimulate insulin secretion: statins as a test case
by: Real, Joana, et al.
Published: (2018)

Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases
by: Zhu, Y., et al.
Published: (2013)

Anti-hyperlipidemic potential of a combination of Zingiber officinale Roscoe, Allium sativum L., Citrus lemon (L.) Osbeck, Honey and Malus domestica Borkh. Cider Vinegar
by: Perumal, Kokila Vani
Published: (2022)

A framework for lipoprotein ontology
by: Chen, Meifania, et al.
Published: (2011)

Exposing hidden putative lipoproteins in Clostridium difficile
by: Griffin, R., et al.
Published: (2017)

Low density lipoprotein cholesterol phenotypes and their association with risk factors of cardiovascular disease among subjects attending health screening at a public university in Malaysia
by: Mazalan, Norlianah
Published: (2019)

Subacute ruminal acidosis reduces sperm quality in beef bulls
by: Callaghan, M.J., et al.
Published: (2016)

Post-prandial lipid metabolism, lipid-modulating agents and cerebrovascular integrity: Implications for dementia risk
by: Pallebage-Gamarallage, Menuka, et al.
Published: (2010)

Elucidating the molecular mechanisms for lipoprotein processing and localisation of Factor H binding protein in Neisseria meningitidis
by: Goncalves da Silva, Ronni Anderson
Published: (2020)

Restoration of dietary-fat induced blood-brain barrier dysfunction by anti-inflammatory lipid-modulating agents
by: Pallebage-Gamarallage, Menuka, et al.
Published: (2012)

Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products
by: Manu, K., et al.
Published: (2013)

Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system
by: Lee, Jong Bong, et al.
Published: (2018)

Plasma Very Low Density Lipoprotein and Fat Deposition in Commercial Broiler and Crossbred Village Chickens
by: Tan, Bee Koon
Published: (2002)

Evaluating inhibitory potential targeting cholesteryl ester transfer protein (CETP) by hydroxycitric acid (HCA) found in garcinia species through kinetic and in-silico technique
by: Abdul Sani, Suraya
Published: (2016)

Mesenteric Lymphatic Targeting of Antiretroviral agents for Improved Treatment of HIV/AIDS
by: Chu, YenJu
Published: (2023)

Potential antioxidant and anti-inflammatory effects of Erythroxylum cuneatum (Miq.) Kurz leaf extract against oxidised low-density lipoprotein in human aortic endothelial cell
by: Shanmugam, Nitya
Published: (2020)

Investigating the effects and mechanisms of HMG-CoA reductase inhibitor simvastatin on the human myometrium
by: Pang, Vincent
Published: (2017)

Impact of replacing red and processed meat with non-meat alternatives on metabolic health
by: Clark, Marie A.
Published: (2017)

Peripheral metabolism of lipoprotein-amyloid beta as a risk factor for Alzheimer's disease: potential interactive effects of APOE genotype with dietary fats
by: D'Alonzo, Zachary, et al.
Published: (2023)

Religious fasting: an alternative approach to improve hyperlipidaemia
by: Khattak, Muhammad Muzaffar Ali Khan, et al.
Published: (2012)

The effect of simvastatin on thromboxane-mediated contraction in porcine coronary artery: investigation of the role of mitochondria and extracellular calcium
by: Saarti, Mohammed
Published: (2019)

Polymeric simvastatin-loaded microsphere delivery system for bone tissue engineering
by: Mohamed, Nur Aliana Hidayah
Published: (2020)

Quality control of herbal medicines in hyperlipidaemia: metabolomics approach
by: Abu Bakar Sajak, Azliana, et al.
Published: (2023)

Analysis of the association between cetp taq1B polymorphism (rs708272) and cholesterol lowering effects among statin users with hyperlipidaemia from HUSM : a pilot study
by: Rahman, Ilani Ab
Published: (2018)

Preventive effects of Moringa oleifera on obesity and hyperlipidaemia : a systematic review
by: Sivanesan Raja Kumar,, et al.
Published: (2022)

Comparison of the neurotoxic and myotoxic effects of two Moroccan scorpion venoms and their neutralization by experimental polyclonal antivenom
by: Oukkache, Naoual, et al.
Published: (2015)

Statin-induced myopathy and the benefit of oral administration of coenzyme Q10
by: Kurniawan, Dede Indra
Published: (2007)

Comparison of the effects of dietary flavonoids and statins on lipopolysaccharide-induced vascular inflammation
by: Alshalmani, Salmin Khalid
Published: (2011)

Factors Influencing Prescribing of Statins in Singapore Compared to Queensland, Australia
by: Curran, R., et al.
Published: (2016)

Barriers to statin use in the Philippines
by: Feliciano, Katrina T, et al.
Published: (2022)

The Silent Classroom: What makes the imbalance?
by: Abdullah, Shamsul
Published: (2009)

Sustainability of External Imbalances: The Case of Malaysia
by: Evan, Lau, et al.
Published: (2003)

Gender Imbalance and The Nigeria’s Democratizing Process
by: Jibril, Abubakar, et al.
Published: (2017)

Sustainability of external imbalances: The case of Malaysia
by: Lau, Evan, et al.
Published: (2003)

Role of meningococcal Neisserial autotransporter lipoprotein (NalP) in host pathogenesis
by: Dufailu, Osman Adamu
Published: (2017)

Legacy effect of delayed blood pressure lowering drug treatment in middle-aged adults with mildly elevated blood pressure: systematic review and meta-analysis
by: Ho, C.L.B., et al.
Published: (2020)

Statins and periodontal inflammation: A pleiotropic effect of statins or a pleiotropic effect of LDL-cholesterol lowering?
by: Norata, Giuseppe, et al.
Published: (2014)

Statins: Antimicrobial resistance breakers or makers?
by: Ko, H., et al.
Published: (2017)