Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans

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Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans

Ageing is associated with impaired hypertrophic responses to resistance exercise training (RET). Here we investigated the aetiology of ‘anabolic resistance’ in older humans. Twenty healthy male individuals, 10 younger (Y; 23 ± 1 years) and 10 older (O; 69 ± 3 years), performed 6 weeks unilateral RET...

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Bibliographic Details
Main Authors:	Brook, Matthew S., Wilkinson, Daniel J., Mitchell, William Kyle, Lund, Jonathan N., Phillips, Bethan E., Szewczyk, Nathaniel J., Greenhaff, Paul L., Smith, Kenneth, Atherton, Philip J.
Format:	Article
Published:	Wiley 2016
Online Access:	https://eprints.nottingham.ac.uk/40212/

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