International criteria for acute kidney injury: advantages and remaining challenges

• Acute Kidney Injury (AKI) is defined using widely accepted international criteria that are based on changes in serum creatinine concentration and degree of oliguria. • AKI, when defined in this way, has a strong association with poor patient outcomes, including high mortality rates and longer hos...

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Main Authors: Selby, Nicholas M., Fluck, Richard J., Kolhe, Nitin V., Taal, Maarten W.
Format: Article
Published: Public Library of Science 2016
Subjects:
Online Access:https://eprints.nottingham.ac.uk/40149/
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author Selby, Nicholas M.
Fluck, Richard J.
Kolhe, Nitin V.
Taal, Maarten W.
author_facet Selby, Nicholas M.
Fluck, Richard J.
Kolhe, Nitin V.
Taal, Maarten W.
author_sort Selby, Nicholas M.
building Nottingham Research Data Repository
collection Online Access
description • Acute Kidney Injury (AKI) is defined using widely accepted international criteria that are based on changes in serum creatinine concentration and degree of oliguria. • AKI, when defined in this way, has a strong association with poor patient outcomes, including high mortality rates and longer hospital admissions with increased resource utilisation and subsequent chronic kidney disease. • The detection of AKI using current criteria can assist with AKI diagnosis and stratification of individual patient risk. • The diagnosis of AKI requires clinical judgement to integrate the definition of AKI with the clinical situation, to determine underlying cause of AKI, and to take account of factors that may affect performance of current definitions.
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spelling nottingham-401492020-05-04T18:12:39Z https://eprints.nottingham.ac.uk/40149/ International criteria for acute kidney injury: advantages and remaining challenges Selby, Nicholas M. Fluck, Richard J. Kolhe, Nitin V. Taal, Maarten W. • Acute Kidney Injury (AKI) is defined using widely accepted international criteria that are based on changes in serum creatinine concentration and degree of oliguria. • AKI, when defined in this way, has a strong association with poor patient outcomes, including high mortality rates and longer hospital admissions with increased resource utilisation and subsequent chronic kidney disease. • The detection of AKI using current criteria can assist with AKI diagnosis and stratification of individual patient risk. • The diagnosis of AKI requires clinical judgement to integrate the definition of AKI with the clinical situation, to determine underlying cause of AKI, and to take account of factors that may affect performance of current definitions. Public Library of Science 2016-09-13 Article PeerReviewed Selby, Nicholas M., Fluck, Richard J., Kolhe, Nitin V. and Taal, Maarten W. (2016) International criteria for acute kidney injury: advantages and remaining challenges. PLOS Medicine, 13 (9). e1002122/1-e1002122/8. ISSN 1549-1676 AKI acute kidney injury; CKD chronic kidney disease; GFR glomerular filtration rate; KDIGO Kidney Disease: Improving Global Outcomes; LMICs low- and middle-income countries; RRT renal replacement therapy http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002122 doi:10.1371/journal.pmed.1002122 doi:10.1371/journal.pmed.1002122
spellingShingle AKI
acute kidney injury; CKD
chronic kidney disease; GFR
glomerular filtration rate; KDIGO
Kidney Disease: Improving Global Outcomes; LMICs
low- and middle-income countries; RRT
renal replacement therapy
Selby, Nicholas M.
Fluck, Richard J.
Kolhe, Nitin V.
Taal, Maarten W.
International criteria for acute kidney injury: advantages and remaining challenges
title International criteria for acute kidney injury: advantages and remaining challenges
title_full International criteria for acute kidney injury: advantages and remaining challenges
title_fullStr International criteria for acute kidney injury: advantages and remaining challenges
title_full_unstemmed International criteria for acute kidney injury: advantages and remaining challenges
title_short International criteria for acute kidney injury: advantages and remaining challenges
title_sort international criteria for acute kidney injury: advantages and remaining challenges
topic AKI
acute kidney injury; CKD
chronic kidney disease; GFR
glomerular filtration rate; KDIGO
Kidney Disease: Improving Global Outcomes; LMICs
low- and middle-income countries; RRT
renal replacement therapy
url https://eprints.nottingham.ac.uk/40149/
https://eprints.nottingham.ac.uk/40149/
https://eprints.nottingham.ac.uk/40149/