Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata
The continuous flow synthesis of a series of amines was successfully achieved by exploiting the enhanced stability and broad substrate scope of an immobilised transaminases from Halomonas elongata (HEWT). A series of substrates were tested in flow reactors and transformed to the corresponding amines...
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| Format: | Article |
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Royal Society of Chemistry
2017
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| Online Access: | https://eprints.nottingham.ac.uk/40105/ |
| _version_ | 1848795985770184704 |
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| author | Planchestainer, Matteo Contente, Martina Letizia Cassidy, Jennifer Molinari, Francesco Tamborini, Lucia Paradisi, Francesca |
| author_facet | Planchestainer, Matteo Contente, Martina Letizia Cassidy, Jennifer Molinari, Francesco Tamborini, Lucia Paradisi, Francesca |
| author_sort | Planchestainer, Matteo |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | The continuous flow synthesis of a series of amines was successfully achieved by exploiting the enhanced stability and broad substrate scope of an immobilised transaminases from Halomonas elongata (HEWT). A series of substrates were tested in flow reactors and transformed to the corresponding amines in good to excellent yields. The process was implemented with an integrated in-line purification step for the recovery of the pure amines. |
| first_indexed | 2025-11-14T19:40:47Z |
| format | Article |
| id | nottingham-40105 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:40:47Z |
| publishDate | 2017 |
| publisher | Royal Society of Chemistry |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-401052020-05-04T18:23:11Z https://eprints.nottingham.ac.uk/40105/ Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata Planchestainer, Matteo Contente, Martina Letizia Cassidy, Jennifer Molinari, Francesco Tamborini, Lucia Paradisi, Francesca The continuous flow synthesis of a series of amines was successfully achieved by exploiting the enhanced stability and broad substrate scope of an immobilised transaminases from Halomonas elongata (HEWT). A series of substrates were tested in flow reactors and transformed to the corresponding amines in good to excellent yields. The process was implemented with an integrated in-line purification step for the recovery of the pure amines. Royal Society of Chemistry 2017-01-01 Article PeerReviewed Planchestainer, Matteo, Contente, Martina Letizia, Cassidy, Jennifer, Molinari, Francesco, Tamborini, Lucia and Paradisi, Francesca (2017) Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata. Green Chemistry, 19 . pp. 372-375. ISSN 1463-9262 http://pubs.rsc.org/en/content/articlehtml/2016/gc/c6gc01780k?page=search doi:10.1039/c6gc01780k doi:10.1039/c6gc01780k |
| spellingShingle | Planchestainer, Matteo Contente, Martina Letizia Cassidy, Jennifer Molinari, Francesco Tamborini, Lucia Paradisi, Francesca Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata |
| title | Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata |
| title_full | Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata |
| title_fullStr | Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata |
| title_full_unstemmed | Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata |
| title_short | Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata |
| title_sort | continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from halomonas elongata |
| url | https://eprints.nottingham.ac.uk/40105/ https://eprints.nottingham.ac.uk/40105/ https://eprints.nottingham.ac.uk/40105/ |