Critical care admission trends and outcomes in individuals with bronchiectasis in the UK

Background: There are limited data on admission trends and outcomes of individuals with bronchiectasis admitted to intensive care (ICU). Using national critical care data, we analysed admissions to ICU and estimated outcomes in terms of mortality in individuals with bronchiectasis and chronic obstru...

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Main Authors: Navaratnam, Vidya, Muirhead, Colin R., Hubbard, Richard B., De Soyza, Anthony
Format: Article
Published: Oxford University Press 2015
Subjects:
Online Access:https://eprints.nottingham.ac.uk/40088/
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author Navaratnam, Vidya
Muirhead, Colin R.
Hubbard, Richard B.
De Soyza, Anthony
author_facet Navaratnam, Vidya
Muirhead, Colin R.
Hubbard, Richard B.
De Soyza, Anthony
author_sort Navaratnam, Vidya
building Nottingham Research Data Repository
collection Online Access
description Background: There are limited data on admission trends and outcomes of individuals with bronchiectasis admitted to intensive care (ICU). Using national critical care data, we analysed admissions to ICU and estimated outcomes in terms of mortality in individuals with bronchiectasis and chronic obstructive pulmonary disease (COPD) admitted to ICU. Methods: Using data from the Intensive Care National Audit and Research Centre, admissions from bronchiectasis and COPD from 1 January 2009 to 31 December 2013 were extracted. Crude admission rates for bronchiectasis and COPD were calculated and Poisson regression was used to estimate unadjusted annual admission rate ratios. We investigated changes to length of stay on ICU, ICU mortality and in-hospital mortality during the study period. We also compared mortality rates in people with bronchiectasis and COPD aged 70 or above. Results: We found an annual increase of 8% (95% Confidence Interval [CI] 2-15) in the number of ICU admissions from bronchiectasis, whilst the yearly increase in ICU admissions from COPD was 1% (95% CI 0.3-2). ICU and in-hospital mortality was higher in individuals with bronchiectasis compared with those with COPD, especially in people aged 70 years or above. Conclusion: Admission to ICU in people with bronchiectasis are uncommon, but are increasing in frequency over time, and carries a substantial mortality rate. This needs to be considered allocating health care resources and planning respiratory services.
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spelling nottingham-400882020-05-04T17:22:45Z https://eprints.nottingham.ac.uk/40088/ Critical care admission trends and outcomes in individuals with bronchiectasis in the UK Navaratnam, Vidya Muirhead, Colin R. Hubbard, Richard B. De Soyza, Anthony Background: There are limited data on admission trends and outcomes of individuals with bronchiectasis admitted to intensive care (ICU). Using national critical care data, we analysed admissions to ICU and estimated outcomes in terms of mortality in individuals with bronchiectasis and chronic obstructive pulmonary disease (COPD) admitted to ICU. Methods: Using data from the Intensive Care National Audit and Research Centre, admissions from bronchiectasis and COPD from 1 January 2009 to 31 December 2013 were extracted. Crude admission rates for bronchiectasis and COPD were calculated and Poisson regression was used to estimate unadjusted annual admission rate ratios. We investigated changes to length of stay on ICU, ICU mortality and in-hospital mortality during the study period. We also compared mortality rates in people with bronchiectasis and COPD aged 70 or above. Results: We found an annual increase of 8% (95% Confidence Interval [CI] 2-15) in the number of ICU admissions from bronchiectasis, whilst the yearly increase in ICU admissions from COPD was 1% (95% CI 0.3-2). ICU and in-hospital mortality was higher in individuals with bronchiectasis compared with those with COPD, especially in people aged 70 years or above. Conclusion: Admission to ICU in people with bronchiectasis are uncommon, but are increasing in frequency over time, and carries a substantial mortality rate. This needs to be considered allocating health care resources and planning respiratory services. Oxford University Press 2015-11-17 Article PeerReviewed Navaratnam, Vidya, Muirhead, Colin R., Hubbard, Richard B. and De Soyza, Anthony (2015) Critical care admission trends and outcomes in individuals with bronchiectasis in the UK. QJM: An International Journal of Medicine, 109 (8). pp. 523-526. ISSN 1460-2725 chronic obstructive airway disease care of intensive care unit patient bronchiectasis hospital mortality intensive care intensive care unit length of stay mortality https://academic.oup.com/qjmed/article-lookup/doi/10.1093/qjmed/hcv206 doi:10.1093/qjmed/hcv206 doi:10.1093/qjmed/hcv206
spellingShingle chronic obstructive airway disease
care of intensive care unit patient
bronchiectasis
hospital mortality
intensive care
intensive care unit
length of stay
mortality
Navaratnam, Vidya
Muirhead, Colin R.
Hubbard, Richard B.
De Soyza, Anthony
Critical care admission trends and outcomes in individuals with bronchiectasis in the UK
title Critical care admission trends and outcomes in individuals with bronchiectasis in the UK
title_full Critical care admission trends and outcomes in individuals with bronchiectasis in the UK
title_fullStr Critical care admission trends and outcomes in individuals with bronchiectasis in the UK
title_full_unstemmed Critical care admission trends and outcomes in individuals with bronchiectasis in the UK
title_short Critical care admission trends and outcomes in individuals with bronchiectasis in the UK
title_sort critical care admission trends and outcomes in individuals with bronchiectasis in the uk
topic chronic obstructive airway disease
care of intensive care unit patient
bronchiectasis
hospital mortality
intensive care
intensive care unit
length of stay
mortality
url https://eprints.nottingham.ac.uk/40088/
https://eprints.nottingham.ac.uk/40088/
https://eprints.nottingham.ac.uk/40088/