Cellular & molecular mechanisms of drug resistance in cancer cells mutated for FBXW7 tumour suppressor gene

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Cellular & molecular mechanisms of drug resistance in cancer cells mutated for FBXW7 tumour suppressor gene

Common anticancer strategies often fail resulting in tumour recurrences and metastasis that cause the majority of cancer-related deaths. Only about 6% of colorectal cancer (CRC) metastatic patients live more than 5 years after diagnosis. Thus, elucidating the crucial mechanisms underlying drug resis...

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Bibliographic Details
Main Author:	Lorenzi, Federica
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2017
Subjects:	Tumour suppressor genes; Drug resistance in cancer cells; Antioncogenes
Online Access:	https://eprints.nottingham.ac.uk/40048/

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