Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter
Rotavirus is an enteric pathogen that causes morbidity and mortality in young mammals, including pigs. Outbreaks of rotavirus on commercial farms have a significant economic impact in terms of losses in production. Effective cleaning and disinfection along with good farm management can reduce rotavi...
| Main Authors: | , |
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| Format: | Article |
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Wiley
2015
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| Online Access: | https://eprints.nottingham.ac.uk/39984/ |
| _version_ | 1848795960200658944 |
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| author | Chandler-Bostock, Rebecca Mellits, K.H. |
| author_facet | Chandler-Bostock, Rebecca Mellits, K.H. |
| author_sort | Chandler-Bostock, Rebecca |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Rotavirus is an enteric pathogen that causes morbidity and mortality in young mammals, including pigs. Outbreaks of rotavirus on commercial farms have a significant economic impact in terms of losses in production. Effective cleaning and disinfection along with good farm management can reduce rotavirus contamination in the environment, and decrease the chance of outbreaks of disease. This study investigated the efficacy of six commercial disinfectants against MS2 bacteriophage and Group A porcine rotavirus, in the presence of high and low levels of organic matter to simulate the farm environment. A phenolic-based disinfectant (Bi-OO-cyst) was effective at all levels of organic matter concentrations. Iodophore based disinfectants did not have a significant virucidal effect against rotavirus under any conditions. For peroxygen compound-based disinfectants and glutaraldehyde-based disinfectants, organic matter load made a significant difference in reducing efficacy. This highlights the importance of thorough cleaning with detergent before disinfection to reduce viral contamination on the farm and decrease rotavirus disease incidence in pigs. |
| first_indexed | 2025-11-14T19:40:23Z |
| format | Article |
| id | nottingham-39984 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:40:23Z |
| publishDate | 2015 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-399842020-05-04T17:21:57Z https://eprints.nottingham.ac.uk/39984/ Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter Chandler-Bostock, Rebecca Mellits, K.H. Rotavirus is an enteric pathogen that causes morbidity and mortality in young mammals, including pigs. Outbreaks of rotavirus on commercial farms have a significant economic impact in terms of losses in production. Effective cleaning and disinfection along with good farm management can reduce rotavirus contamination in the environment, and decrease the chance of outbreaks of disease. This study investigated the efficacy of six commercial disinfectants against MS2 bacteriophage and Group A porcine rotavirus, in the presence of high and low levels of organic matter to simulate the farm environment. A phenolic-based disinfectant (Bi-OO-cyst) was effective at all levels of organic matter concentrations. Iodophore based disinfectants did not have a significant virucidal effect against rotavirus under any conditions. For peroxygen compound-based disinfectants and glutaraldehyde-based disinfectants, organic matter load made a significant difference in reducing efficacy. This highlights the importance of thorough cleaning with detergent before disinfection to reduce viral contamination on the farm and decrease rotavirus disease incidence in pigs. Wiley 2015-11-22 Article PeerReviewed Chandler-Bostock, Rebecca and Mellits, K.H. (2015) Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter. Letters in Applied Microbiology, 61 (6). pp. 538-543. ISSN 1472-765X http://onlinelibrary.wiley.com/doi/10.1111/lam.12502/abstract doi:10.1111/lam.12502 doi:10.1111/lam.12502 |
| spellingShingle | Chandler-Bostock, Rebecca Mellits, K.H. Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter |
| title | Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter |
| title_full | Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter |
| title_fullStr | Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter |
| title_full_unstemmed | Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter |
| title_short | Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter |
| title_sort | efficiency of disinfectants against rotavirus in the presence and absence of organic matter |
| url | https://eprints.nottingham.ac.uk/39984/ https://eprints.nottingham.ac.uk/39984/ https://eprints.nottingham.ac.uk/39984/ |