Detection of modified forms of cytosine using sensitive
immunohistochemistry

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Detection of modified forms of cytosine using sensitive immunohistochemistry

Methylation of cytosine bases (5-methylcytosine, 5mC) occurring in vertebrate genomes is usually associated with transcriptional silencing. 5-hydroxylmethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) are the recently discovered modified cytosine bases produced by enzymatic...

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Bibliographic Details
Main Authors:	Abakir, Abdulkadir, Wheldon, Lee M., Johnson, Andrew D., Laurent, Patrick, Ruzov, Alexey
Format:	Article
Published:	Journal of Visualized Experiments 2016
Subjects:	Molecular Biology Issue 114 Brain tissues DNA methylation (5mC) DNA demethylation 5-hydroxymethylcytosine (5hmC) 5- formylcytosine (5fC) 5-carboxylcytosine (5caC) Immunohistochemistry Signal amplification Immunofluorescence
Online Access:	https://eprints.nottingham.ac.uk/39950/

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