Quantitative analysis of lab-to-lab variability in Caco-2 permeability assays

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Quantitative analysis of lab-to-lab variability in Caco-2 permeability assays

In this study, Caco-2 permeability results from different laboratories were compared. Six different sets of apparent permeability coefficient (Papp) values reported in the literature were compared to experimental Papp obtained in our laboratory. The differences were assessed by determining the root...

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Bibliographic Details
Main Authors:	Lee, Jong Bong, Zgair, Atheer, Taha, Dhiaa A., Zang, Xiaowei, Kagan, Leonid, Kim, Tae Hwan, Kim, Min Gi, Yun, Hwi-yeol, Fischer, Peter M., Gershkovich, Pavel
Format:	Article
Published:	Elsevier 2017
Subjects:	Drug permeability; Caco-2 permeability assay; Lab-to-lab variability; Prediction of oral absorption; GastroPlus
Online Access:	https://eprints.nottingham.ac.uk/39895/

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