Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival

Impaired apoptosis is one of the hallmarks of cancer. Caspase-3 and -8 are key regulators of the apoptotic response and have been shown to interact with the calpain family, a group of cysteine proteases, during tumorigenesis. The current study sought to investigate the prognostic potential of caspas...

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Bibliographic Details
Main Authors: Xuan, Pu, Storr, Sarah J., Zhang, Yimin, Rakha, Emad, Green, Andrew R., Ellis, Ian O., Martin, Stewart G.
Format: Article
Published: Springer Verlag 2016
Subjects:
Online Access:https://eprints.nottingham.ac.uk/39796/