Physical and biological characteristics of multi drug resistance (MDR): an integral approach considering pH and drug resistance in cancer

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Physical and biological characteristics of multi drug resistance (MDR): an integral approach considering pH and drug resistance in cancer

The role of the Warburg effect in cancer remains to be elucidated with a resurgence in research efforts over the past decade. Why a cancer cell would prefer to use energy inefficient glycolysis, leading to an alteration of pH both inside and outside of the cell, remains to be uncovered. The developm...

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Bibliographic Details
Main Authors:	Omran, Ziad, Scaife, Paula, Stewart, Simon, Rauch, Cyril
Format:	Article
Published:	Elsevier 2017
Subjects:	Pharmacokinetic; Drug transporter; Membrane biophysics; Warburg effect
Online Access:	https://eprints.nottingham.ac.uk/39780/

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