Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism

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Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism

AIM: To evaluate the effects of the non-selective, non-steroidal anti-inflammatory drug (NSAID) acetylsalicylic acid (ASA), on ex vivo embryonic kidney growth and development. METHODS: Pairs of fetal mouse kidneys at embryonic day 12.5 were cultured ex vivo in increasing concentrations of ASA (0.04...

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Bibliographic Details
Main Authors:	Welham, Simon J.M., Sparrow, Alexander J., Gardner, David S., Elmes, Matthew J.
Format:	Article
Published:	Baishideng Publishing Group Inc 2017
Subjects:	Acetylsalicylic acid; Nephrogenesis; Kidney culture; Non-steroidal anti-inflammatory drug; Prostaglandins; Prostaglandin synthase 2
Online Access:	https://eprints.nottingham.ac.uk/39734/

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