Transaminase triggered aza-Michael approach for the enantioselective synthesis of piperidine scaffolds

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Transaminase triggered aza-Michael approach for the enantioselective synthesis of piperidine scaffolds

The expanding “toolbox” of biocatalysts opens new opportunities to redesign synthetic strategies to target molecules by incorporating a key enzymatic step into the synthesis. Herein, we describe a general biocatalytic approach for the enantioselective preparation of 2,6-disubstituted piperidines sta...

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Bibliographic Details
Main Authors:	Ryan, James, Šiaučiulis, Mindaugas, Gomm, Andrew, Macia, Beatriz, O'Reilly, Elaine, Caprio, Vittorio
Format:	Article
Published:	American Chemical Society 2016
Online Access:	https://eprints.nottingham.ac.uk/39699/

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