Development of miRNA-mimic nanoparticles for the treatment of brain tumours

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Development of miRNA-mimic nanoparticles for the treatment of brain tumours

Glioblastoma are aggressive brain tumours with a median survival of 15 months even with the best currently available treatment options. microRNAs (miRNA) are ~23 nucleotide natural silencing RNAs that have great potentials to improve cancer treatment outcomes. Lack of a safe, stable and efficient de...

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Bibliographic Details
Main Author:	Anithiya Ramamoorthi Gopalram, Shubaash
Format:	Thesis (University of Nottingham only)
Language:	English English
Published:	2017
Subjects:	miRNA Delivery Glioblastoma Poly(amidoamine) thiol crosslinking ligand targeting nanomedicine luciferase assay RNA interference.
Online Access:	https://eprints.nottingham.ac.uk/39449/

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