A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

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A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

Introduction: We hypothesized that common Alzheimer's disease (AD)-associated variants within the triggering receptor expressed on myeloid (TREM) gene cluster influence disease through gene expression. Methods: Expression microarrays on temporal cortex and cerebellum from ∼400 neuropathologi...

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Bibliographic Details
Main Authors:	Carrasquillo, Minerva, Allen, Mariet, Burgess, Jeremy D., Medway, Christopher, Morgan, Kevin
Format:	Article
Published:	Elsevier 2017
Subjects:	Alzheimer's disease; eQTL; TREM2; TREML1; Regulatory variant
Online Access:	https://eprints.nottingham.ac.uk/39400/

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