Determination of agonist intrinsic efficacies at the dopamine D2 receptor

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Determination of agonist intrinsic efficacies at the dopamine D2 receptor

G protein coupled receptor agonists can be described by two parameters; affinity (ability to bind a receptor) and efficacy (ability to activate a receptor once bound). While affinity is now an accessible parameter through binding studies, agonist efficacies have historically been difficult to determ...

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Bibliographic Details
Main Author:	Stott, Lisa Alice
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2017
Subjects:	Agonist functional responses Dopamine D2 receptor Dopamine agonists
Online Access:	https://eprints.nottingham.ac.uk/39305/

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