Adverse effects of anti-tuberculosis drugs on HepG2 cell
bioenergetics

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Adverse effects of anti-tuberculosis drugs on HepG2 cell bioenergetics

Tuberculosis (TB) is an intractable chronic infection. Disease treatment with anti-TB drugs remains challenging due to drug-induced hepatotoxicity. The toxicity of the anti-TB drugs rifampicin (RIF), isoniazid (INH) and pyrazinamide (PZA) either alone or in combination was investigated in HepG2 cell...

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Bibliographic Details
Main Authors:	Elmorsy, E., Attalla, S.M., Fikry, E., Kocon, A., Turner, R., Christie, D., Warren, A., Nwidu, Lucky Legbosi, Carter, Wayne
Format:	Article
Published:	SAGE 2016
Subjects:	anti-TB drugs drug-induced hepatoxicity mitachondrial complex I and complex III activity mitochondrial membrane potential mitophany
Online Access:	https://eprints.nottingham.ac.uk/39181/

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