Imprinted contact lenses for sustained release of polymyxin B and related antimicrobial peptides

QR Code

Imprinted contact lenses for sustained release of polymyxin B and related antimicrobial peptides

The aim of this work was to develop drug-soft contact lens combination products suitable for controlled release of antimicrobial peptides on the ocular surface. Incorporation of functional monomers and the application of molecular imprinting techniques were explored to endow 2-hydroxyethyl methacryl...

Full description

Bibliographic Details
Main Authors:	Malakooti, Negin, Alexander, Cameron, Alvarez-Lorenzo, Carmen
Format:	Article
Published:	Elsevier 2015
Subjects:	Hydrogels; Biomaterials; Controlled release; Peptide delivery; Mucosal delivery; Drug-device combination product; Molecular imprinting; Ophthalmic drug delivery; Contact lens; Pseudomonas aeruginosa
Online Access:	https://eprints.nottingham.ac.uk/39083/

Similar Items

Correlating drug release with microstructure of hydrogel-based delivery systems
by: Prasittisart, Pundarik
Published: (2020)

Improving Nanoparticle Drug loading: Matching Polymer to Drug Properties and making of Polymer coated Drug Nanoparticles
by: ANIMASAWUN, R.K
Published: (2020)

New antimicrobial biomaterials based on recombinant spider silks
by: Beinarovica, Jolanta
Published: (2022)

A study of microparticle shape and surface chemistry effects on interactions with macrophages
by: Bruce, Gordon
Published: (2021)

Nanocapsules loaded hydrogels for intra-articular and intra-peritoneal drug delivery
by: Surikutchi, Bhanu Teja
Published: (2020)

Inkjet printing of solid oral dosage forms
by: Cader, Hatim K.
Published: (2019)

Optimization of aptamer-based manganese doped zinc sulphide/chitosan and carbon dots/chitosan as drug nanocarriers for controlled release of Mitomycin C
by: Abd Manan, Fariza Aina
Published: (2024)

Cationic supramolecular hydrogels for overcoming the skin barrier in drug delivery
by: Limon, David, et al.
Published: (2017)

Synthesis, characterization and cytotoxicity evaluation of carboxylated carbon nanotubes functionalized with silibinin, betulinic acid and levodopa for drug delivery
by: Tan, Julia Meihua
Published: (2015)

Understanding the Lung Disposition of Inhaled Compounds using the Bronchial Epithelial Cell Culture Model Calu-3
by: Panduga, Vijender
Published: (2019)

Rational engineering of Apoferritin-based nanoparticles for drug delivery
by: Crowhurst, Samuel
Published: (2025)

Gradient delivery of bioactive molecules across porous hydrogels
by: Eltaher, Hoda M.M.A.
Published: (2016)

Microfluidic-Assisted Nanoprecipitation to Produce Personalised Dosage Forms
by: Hosseini, Sarvenaz
Published: (2022)

Improving drug delivery to the lungs as a function of excipient choice
by: Olubi, Rebecca
Published: (2024)

Recombinant spider silk protein hydrogels
by: Earlam, Rowan
Published: (2021)

Poly(lactic acid)-poly(ethylene glycol) copolymers for use as drug delivery systems
by: Hagan, Susan Anne
Published: (1998)

Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against glioblastoma
by: Smith, Stuart J., et al.
Published: (2014)

Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against glioblastoma
by: Smith, Stuart J., et al.
Published: (2014)

Synthesis and Evaluation of Lung Tissue Retentive Prodrugs
by: Ayre, Jack
Published: (2022)

Development of Novel Apoferritin Formulations for Antitumour Benzothiazoles
by: Breen, Alastair F
Published: (2019)

Transdermal insulin on demand
by: Smith, Fiona
Published: (2024)

Mechanistic insights into the self-assembly and the interactions of supramolecular gels with biological systems
by: Angelerou, Maria G. F.
Published: (2019)

Three-dimensional flower-like brushite crystals prepared from high internal phase emulsion for drug delivery application
by: Hong, Ngee Lim, et al.
Published: (2009)

Development and in vitro bioevaluation of cockle shell-calcium carbonate (Aragonite) nanoparticles for intracellular drug delivery
by: Isa, Tijani
Published: (2015)

Development of multifunctional drug delivery systems based on virus-like nanoparticles for cancer targeting drug delivery
by: Biabanikhankahdani, Roya
Published: (2017)

Synthesis and in-vitro toxicity evaluation of anticancer drugs-loaded chitosan nanoparticles as therapeutic nanocarriers for the treatment of hepatocellular carcinoma
by: Mohammed, Albalawi Fahad
Published: (2023)

Identification of novel ‘inks’ for 3D printing using high throughput screening: bioresorbable photocurable polymers for controlled drug delivery
by: Louzao, Iria, et al.
Published: (2018)

Formulation of chitosan-based nanoparticles for delivery of proteins and peptides
by: Vellore Janarthanan, Mohanraj
Published: (2003)

Design and development of injectable intraperitoneal sustained release drug delivery system for ovarian cancer
by: Nazir, Chaudhry Zahid
Published: (2020)

Graphene oxide-gallic acid nanodelivery system for cancer therapy
by: Dorniani, Dena, et al.
Published: (2016)

Understanding the contribution of Resistance-Nodulation-Division family efflux pumps to the lifestyle of Pseudomonas aeruginosa
by: Scales, Danielle
Published: (2023)

3D spheroid models for in vitro evaluation of nanoparticles for cancer therapy
by: Tchoryk, Aleksandra
Published: (2018)

Developing a sprayable drug delivery system for the local delivery of nanoparticles in glioblastoma multiforme
by: McCrorie, Phoebe
Published: (2021)

Nucleoside based self-assembling drugs for localized drug delivery
by: Skilling, Kathryn J., et al.
Published: (2018)

Development of nanoparticles for targeted delivery of p38 MAPK inhibitor to myeloid dendritic cells
by: You, Jinge
Published: (2024)

Apoferritin delivery of imidazotetrazine agents for targeted brain tumour therapy
by: Bouzinab, Kaouthar
Published: (2021)

Predicting physical stability of pharmaceuticals and investigating use of Raman spectroscopy to interrogate molecular relaxation events
by: Lee, Para
Published: (2023)

Development of a drug delivery agent based on ionic liquids templated mesoporous silica nanoparticles
by: Mohamed Isa, Eleen Dayana
Published: (2017)

Functionalized ionic-liquid templated mesoporous silica nanoparticles for anticancer drug delivery system
by: Zaharudin, Nurul Syahira
Published: (2018)

Development of nanoemulsion containing Centella asiatica (L.) Urb crude extract as a promising drug delivery system for epilepsy treatment
by: L. Thuraisingam, Shobna
Published: (2021)