Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration
There is a growing interest in the therapeutic utility of compounds derived from Curcuma longa, an herb of the Zingiberaceae family that has been part of traditional medicine for centuries. Recent reports suggest that bioactive compounds isolated from the rhizome of these plants can address two key...
| Main Authors: | , |
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| Format: | Article |
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American Diabetes Association
2014
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| Online Access: | https://eprints.nottingham.ac.uk/39004/ |
| _version_ | 1848795739319173120 |
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| author | Poser, Stephen W. Androutsellis-Theotokis, Andreas |
| author_facet | Poser, Stephen W. Androutsellis-Theotokis, Andreas |
| author_sort | Poser, Stephen W. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | There is a growing interest in the therapeutic utility of compounds derived from Curcuma longa, an herb of the Zingiberaceae family that has been part of traditional medicine for centuries. Recent reports suggest that bioactive compounds isolated from the rhizome of these plants can address two key aspects of brain injury following stroke that must be dealt with for functional recovery to occur: the moderation of neuroinflammation, and the mobilization of endogenous stem cells resident in the nervous system. Defining their mechanism of action remains a question, but emerging evidence may point towards one shared with more classic modulators of neural stem cell proliferation and survival. |
| first_indexed | 2025-11-14T19:36:52Z |
| format | Article |
| id | nottingham-39004 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:36:52Z |
| publishDate | 2014 |
| publisher | American Diabetes Association |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-390042020-05-04T16:57:23Z https://eprints.nottingham.ac.uk/39004/ Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration Poser, Stephen W. Androutsellis-Theotokis, Andreas There is a growing interest in the therapeutic utility of compounds derived from Curcuma longa, an herb of the Zingiberaceae family that has been part of traditional medicine for centuries. Recent reports suggest that bioactive compounds isolated from the rhizome of these plants can address two key aspects of brain injury following stroke that must be dealt with for functional recovery to occur: the moderation of neuroinflammation, and the mobilization of endogenous stem cells resident in the nervous system. Defining their mechanism of action remains a question, but emerging evidence may point towards one shared with more classic modulators of neural stem cell proliferation and survival. American Diabetes Association 2014-11-17 Article PeerReviewed Poser, Stephen W. and Androutsellis-Theotokis, Andreas (2014) Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration. Stem Cell Research & Therapy, 5 (6). p. 127. ISSN 1939-327X http://stemcellres.biomedcentral.com/articles/10.1186/scrt517 doi:10.1186/scrt517 doi:10.1186/scrt517 |
| spellingShingle | Poser, Stephen W. Androutsellis-Theotokis, Andreas Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration |
| title | Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration |
| title_full | Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration |
| title_fullStr | Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration |
| title_full_unstemmed | Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration |
| title_short | Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration |
| title_sort | spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration |
| url | https://eprints.nottingham.ac.uk/39004/ https://eprints.nottingham.ac.uk/39004/ https://eprints.nottingham.ac.uk/39004/ |