Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells

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Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells

Determination of defined roles for endogenous homeobox (Hox) genes in adult hematopoietic stem and progenitor cell (HSPC) activity has been hampered by a combination of embryonic defects and functional redundancy. Here we show that conditional homozygous deletion of the Hoxa cluster (Hoxa−/−) result...

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Bibliographic Details
Main Authors:	Lebert-Ghali, Charles-Étienne, Fournier, Marilaine, Kettyle, Laura M.J., Thompson, Alexander, Sauvageau, Guy, Bijl, Janet J.
Format:	Article
Published:	American Society of Hematology 2016
Online Access:	https://eprints.nottingham.ac.uk/38605/

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