Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves

The objective of this cohort study was to assess the relationship between perinatal calf management practices relevant to the control of paratuberculosis and passive transfer of immunoglobulin in calves born in an endemically infected Irish dairy herd. Data from 176 calves were used to assess the ef...

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Main Authors: McAloon, Conor G., Whyte, Paul, O'Grady, L., Lorenz, I., Green, Martin J., Hogan, I., Johnson, A., Doherty, Michael L.
Format: Article
Published: BMJ Publishing Group 2016
Online Access:https://eprints.nottingham.ac.uk/38583/
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author McAloon, Conor G.
Whyte, Paul
O'Grady, L.
Lorenz, I.
Green, Martin J.
Hogan, I.
Johnson, A.
Doherty, Michael L.
author_facet McAloon, Conor G.
Whyte, Paul
O'Grady, L.
Lorenz, I.
Green, Martin J.
Hogan, I.
Johnson, A.
Doherty, Michael L.
author_sort McAloon, Conor G.
building Nottingham Research Data Repository
collection Online Access
description The objective of this cohort study was to assess the relationship between perinatal calf management practices relevant to the control of paratuberculosis and passive transfer of immunoglobulin in calves born in an endemically infected Irish dairy herd. Data from 176 calves were used to assess the effect of time spent in the calving area, individual versus non-designated calving and colostrum pasteurisation on serum total protein, zinc sulphate turbidity, globulin and γ-glutamyltransferase. In addition, the effects of colostrum quality, volume of colostrum fed, method of colostrum administration and calving season on passive transfer were quantified. Serum samples were collected as part of routine herd health monitoring from calves aged between one and seven days. Multivariate linear and logistic regression models were used to assess the effect of each variable on the test result and failure of passive transfer as determined using a cut-off point for each diagnostic test. Colostrum pasteurisation and calving area were not significantly associated with passive transfer, whereas increased time spent in the calving pen was consistently associated with a detrimental effect. In addition, a strong seasonal effect was apparent, which appeared to be unrelated to colostrum quality and calf management. The authors are unaware of published studies documenting such a significant seasonal effect on passive transfer.
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spelling nottingham-385832020-05-04T17:57:53Z https://eprints.nottingham.ac.uk/38583/ Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves McAloon, Conor G. Whyte, Paul O'Grady, L. Lorenz, I. Green, Martin J. Hogan, I. Johnson, A. Doherty, Michael L. The objective of this cohort study was to assess the relationship between perinatal calf management practices relevant to the control of paratuberculosis and passive transfer of immunoglobulin in calves born in an endemically infected Irish dairy herd. Data from 176 calves were used to assess the effect of time spent in the calving area, individual versus non-designated calving and colostrum pasteurisation on serum total protein, zinc sulphate turbidity, globulin and γ-glutamyltransferase. In addition, the effects of colostrum quality, volume of colostrum fed, method of colostrum administration and calving season on passive transfer were quantified. Serum samples were collected as part of routine herd health monitoring from calves aged between one and seven days. Multivariate linear and logistic regression models were used to assess the effect of each variable on the test result and failure of passive transfer as determined using a cut-off point for each diagnostic test. Colostrum pasteurisation and calving area were not significantly associated with passive transfer, whereas increased time spent in the calving pen was consistently associated with a detrimental effect. In addition, a strong seasonal effect was apparent, which appeared to be unrelated to colostrum quality and calf management. The authors are unaware of published studies documenting such a significant seasonal effect on passive transfer. BMJ Publishing Group 2016-06-03 Article PeerReviewed McAloon, Conor G., Whyte, Paul, O'Grady, L., Lorenz, I., Green, Martin J., Hogan, I., Johnson, A. and Doherty, Michael L. (2016) Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves. Veterinary Record, 179 (2). p. 47. ISSN 2042-7670 http://veterinaryrecord.bmj.com/content/179/2/47 10.1136/vr.103547 10.1136/vr.103547 10.1136/vr.103547
spellingShingle McAloon, Conor G.
Whyte, Paul
O'Grady, L.
Lorenz, I.
Green, Martin J.
Hogan, I.
Johnson, A.
Doherty, Michael L.
Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves
title Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves
title_full Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves
title_fullStr Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves
title_full_unstemmed Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves
title_short Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves
title_sort relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves
url https://eprints.nottingham.ac.uk/38583/
https://eprints.nottingham.ac.uk/38583/
https://eprints.nottingham.ac.uk/38583/