Highly pathogenic avian influenza H5N6 viruses exhibit enhanced affinity for human type sialic acid receptor and in-contact transmission in model ferrets

QR Code

Highly pathogenic avian influenza H5N6 viruses exhibit enhanced affinity for human type sialic acid receptor and in-contact transmission in model ferrets

Since May 2014, highly pathogenic avian influenza H5N6 virus has been reported to cause six severe human infections three of which were fatal. The biological properties of this subtype, in particular its relative pathogenicity and transmissibility in mammals, are not known. We characterized the viru...

Full description

Bibliographic Details
Main Authors:	Sun, Honglei, Pu, Juan, Wei, Yandi, Sun, Yipeng, Hu, Jiao, Liu, Litao, Xu, Guanlong, Gao, Weihua, Li, Chong, Zhang, Xuxiao, Huang, Yinhua, Chang, Kin-Chow, Liu, Xiufan, Liu, Jinhua
Format:	Article
Published:	American Society for Microbiology 2016
Online Access:	https://eprints.nottingham.ac.uk/38539/

Similar Items

Prevailing PA mutation K356R in avian influenza H9N2 virus increases mammalian replication and pathogenicity
by: Xu, Guanlong, et al.
Published: (2016)

PA-X is a virulence factor in avian H9N2 influenza virus
by: Gao, Huijie, et al.
Published: (2015)

Enhanced pathogenicity and neurotropism of mouse-adapted H10N7 influenza virus are mediated by novel PB2 and NA mutations
by: Zhang, Xuxiao, et al.
Published: (2017)

The contribution of PA-X to the virulence of pandemic 2009 H1N1 and highly pathogenic H5N1 avian influenza viruses
by: Gao, Huijie, et al.
Published: (2015)

M gene reassortment in H9N2 influenza virus promotes early infection and replication: contribution to rising virus prevalence in chickens in China
by: Pu, Juan, et al.
Published: (2017)

Transmission and pathogenicity of novel reassortants derived from Eurasian avian-like and 2009 pandemic H1N1 influenza viruses in mice and guinea pigs
by: Kong, Weili, et al.
Published: (2016)

Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity
by: Gao, Huijie, et al.
Published: (2015)

Assessment of avian erythrocytes that exhibit variant nuclear morphology
by: Clark, Phillip
Published: (2015)

Gender and the pursuit of small prey: archaeological, historical and iconographic perspectives on trapping, falconry and ferreting
by: Fowler, Thomas A.
Published: (2016)

Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and proinflammatory dysregulation
by: Chang, Pengxiang, et al.
Published: (2015)

Expression and purification of hemagglutinin and neuraminidase recombinant protein of avian influenza a virus using immobilised metal affinity chromatography (imac)
by: Chiang, Goh Wei
Published: (2016)

Malacca to hold exhibition on Hang Tuah
by: The Sun, .
Published: (2024)

Comparative virus replication and host innate responses in human cells infected with three prevalent clades (2.3.4, 2.3.2, and 7) of highly pathogenic avian influenza H5N1 viruses
by: Sun, H., et al.
Published: (2014)

Combinatorial Design Of Virtual Sialic Acid Analogues Against Influenza A Hemagglutinin Using Structure And Fragment Based Approaches
by: Al-Qattan, Mohammed Noor Al-Deen
Published: (2009)

Detection of avian influenza virus.
by: Omar, Abdul Rahman, et al.
Published: (2006)

Retention of sialic acid content in Malaysian edible bird's nest by heat pump drying
by: Gan, Shu Hui, et al.
Published: (2017)

A study of the biochemical development and toxicology of the seed of Santalum spicatum.
by: Liu, Yandi
Published: (1997)

Fuzzy based affinity learning for spectral clustering
by: Li, Q., et al.
Published: (2016)

Affinity learning via a diffusion process for subspace clustering
by: Li, Q., et al.
Published: (2018)

Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function
by: Betteridge, Kai, et al.
Published: (2017)

Kinetic retention of sialic acid and antioxidants in Malaysian edible bird's nest during low-temperature drying
by: Gan, Shu Hui, et al.
Published: (2017)

The potential use of sialic acid from edible bird’s nest to attenuate mitochondrial dysfunction by in vitro study
by: Abd Rashed, Aswir, et al.
Published: (2021)

Affinity
by: Tan, Elizabeth
Published: (2010)

Effects of sialic acid from edible bird nest on cell viability associated with brain cognitive performance in mice
by: Abdul Khalid, Siti Khadijah, et al.
Published: (2019)

Cost-effective drying methods for edible bird’s nest hydrolysate: Impact on nitrite levels and sialic acid content
by: Yeo, Bee Hui, et al.
Published: (2024)

Detection of avian influenza A virus in Malaysian birds
by: Rahim, Z.A, et al.
Published: (2015)

LS-SVM approximate solution for affine nonlinear systems with partially unknown functions
by: Zhang, G., et al.
Published: (2014)

Naturally occurring mutations in the PA gene are key contributors to increased virulence of pandemic H1N1/09 influenza virus in mice
by: Sun, Y., et al.
Published: (2014)

A strategy of global convergence for the affine scaling algorithm for convex semidefinite programming
by: Qian, X., et al.
Published: (2018)

Plant-based vaccines for poultry viral diseases: Avian influenza
by: Elbohy, Ola Assem Mohamed Saleh
Published: (2023)

A qualitative stakeholder analysis of avian influenza policy in Bangladesh
by: Chattopadhyay, Kaushik, et al.
Published: (2017)

In Vitro And In Vivo Studies Of Malaysian Isolates Of Avian Influenza Virus
by: Ibrahim, Harith Mohammad
Published: (1993)

Optimal control of piecewise affine systems with piecewise affine state feedback
by: Wu, C., et al.
Published: (2009)

Avian influenza: global assessment of potential pandemic of the twenty first century
by: Abubakar, Mustapha Bala, et al.
Published: (2009)

Epidemiology Of Influenza A Viruses In The Avian And Swine Populations In Peninsular Malaysia
by: Ramiah, Suriya Kumari
Published: (2008)

Exhibiting on the Edge
by: Farren, Anne
Published: (2011)

The activity of avian rhodanese
by: Oh, S. Y., et al.
Published: (1977)

Avian-centric design
by: Abdul Shukor, Shureen Faris
Published: (2015)

Cancer profiles by Affinity Propagation
by: Soria, Daniele, et al.
Published: (2009)

Cancer profiles by affinity propagation
by: Ambrogi, Federico, et al.
Published: (2008)