Assessment of a rapid liquid-based cytology method for measuring sputum cell counts
Differential sputum cell counting is not widely available despite proven clinical utility in the management of asthma. We compared eosinophil counts obtained using liquid-based cytology (LBC), a routine histopathological processing method, and the current standard method. Eosinophil counts obtained...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Published: |
BMJ Publishing Group
2016
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| Online Access: | https://eprints.nottingham.ac.uk/38383/ |
| _version_ | 1848795599488417792 |
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| author | Martin, M.J. Lee, H. Meakin, G. Green, A. Simms, R.L. Reynolds, C. Winters, S. Shaw, Dominick E. Soomro, Irshad N. Harrison, Timothy W. |
| author_facet | Martin, M.J. Lee, H. Meakin, G. Green, A. Simms, R.L. Reynolds, C. Winters, S. Shaw, Dominick E. Soomro, Irshad N. Harrison, Timothy W. |
| author_sort | Martin, M.J. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Differential sputum cell counting is not widely available despite proven clinical utility in the management of asthma. We compared eosinophil counts obtained using liquid-based cytology (LBC), a routine histopathological processing method, and the current standard method. Eosinophil counts obtained using LBC were a strong predictor of sputum eosinophilia (≥3%) determined by the standard method suggesting LBC could be used in the management of asthma. |
| first_indexed | 2025-11-14T19:34:39Z |
| format | Article |
| id | nottingham-38383 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:34:39Z |
| publishDate | 2016 |
| publisher | BMJ Publishing Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-383832020-05-04T18:07:32Z https://eprints.nottingham.ac.uk/38383/ Assessment of a rapid liquid-based cytology method for measuring sputum cell counts Martin, M.J. Lee, H. Meakin, G. Green, A. Simms, R.L. Reynolds, C. Winters, S. Shaw, Dominick E. Soomro, Irshad N. Harrison, Timothy W. Differential sputum cell counting is not widely available despite proven clinical utility in the management of asthma. We compared eosinophil counts obtained using liquid-based cytology (LBC), a routine histopathological processing method, and the current standard method. Eosinophil counts obtained using LBC were a strong predictor of sputum eosinophilia (≥3%) determined by the standard method suggesting LBC could be used in the management of asthma. BMJ Publishing Group 2016-08-08 Article PeerReviewed Martin, M.J., Lee, H., Meakin, G., Green, A., Simms, R.L., Reynolds, C., Winters, S., Shaw, Dominick E., Soomro, Irshad N. and Harrison, Timothy W. (2016) Assessment of a rapid liquid-based cytology method for measuring sputum cell counts. Thorax . ISSN 1468-3296 http://thorax.bmj.com/content/early/2016/08/08/thoraxjnl-2016-208817.abstract doi:10.1136/thoraxjnl-2016-208817 doi:10.1136/thoraxjnl-2016-208817 |
| spellingShingle | Martin, M.J. Lee, H. Meakin, G. Green, A. Simms, R.L. Reynolds, C. Winters, S. Shaw, Dominick E. Soomro, Irshad N. Harrison, Timothy W. Assessment of a rapid liquid-based cytology method for measuring sputum cell counts |
| title | Assessment of a rapid liquid-based cytology method for measuring sputum cell counts |
| title_full | Assessment of a rapid liquid-based cytology method for measuring sputum cell counts |
| title_fullStr | Assessment of a rapid liquid-based cytology method for measuring sputum cell counts |
| title_full_unstemmed | Assessment of a rapid liquid-based cytology method for measuring sputum cell counts |
| title_short | Assessment of a rapid liquid-based cytology method for measuring sputum cell counts |
| title_sort | assessment of a rapid liquid-based cytology method for measuring sputum cell counts |
| url | https://eprints.nottingham.ac.uk/38383/ https://eprints.nottingham.ac.uk/38383/ https://eprints.nottingham.ac.uk/38383/ |