Detection of a Yersinia pestisgene homologue in rodent samples
A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platform to screen for zoonotic pathogens of interest. S...
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| Format: | Article |
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PeerJ
2016
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| Online Access: | https://eprints.nottingham.ac.uk/38074/ |
| _version_ | 1848795591348322304 |
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| author | Giles, Timothy A. Greenwood, Alex D. Tsangaras, Kyriakos Giles, Tom C. Barrow, Paul A. Hannant, Duncan Abu-Median, Abu-Bakr Yon, Lisa |
| author_facet | Giles, Timothy A. Greenwood, Alex D. Tsangaras, Kyriakos Giles, Tom C. Barrow, Paul A. Hannant, Duncan Abu-Median, Abu-Bakr Yon, Lisa |
| author_sort | Giles, Timothy A. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platform to screen for zoonotic pathogens of interest. Samples were from urban locations in the UK (Liverpool) and Canada (Vancouver). The results indicate the presence of an unknown bacterium that shares a homologue for the pla gene of Yersinia pestis, so caution should be taken when using this gene as a diagnostic marker. |
| first_indexed | 2025-11-14T19:34:31Z |
| format | Article |
| id | nottingham-38074 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:34:31Z |
| publishDate | 2016 |
| publisher | PeerJ |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-380742020-05-04T18:06:43Z https://eprints.nottingham.ac.uk/38074/ Detection of a Yersinia pestisgene homologue in rodent samples Giles, Timothy A. Greenwood, Alex D. Tsangaras, Kyriakos Giles, Tom C. Barrow, Paul A. Hannant, Duncan Abu-Median, Abu-Bakr Yon, Lisa A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platform to screen for zoonotic pathogens of interest. Samples were from urban locations in the UK (Liverpool) and Canada (Vancouver). The results indicate the presence of an unknown bacterium that shares a homologue for the pla gene of Yersinia pestis, so caution should be taken when using this gene as a diagnostic marker. PeerJ 2016-08-17 Article PeerReviewed Giles, Timothy A., Greenwood, Alex D., Tsangaras, Kyriakos, Giles, Tom C., Barrow, Paul A., Hannant, Duncan, Abu-Median, Abu-Bakr and Yon, Lisa (2016) Detection of a Yersinia pestisgene homologue in rodent samples. PeerJ, 4 . e2216/1-e2216/9. ISSN 2167-8359 Yersinia pestis Rodents Screening Microarray https://peerj.com/articles/2216/ doi:10.7717/peerj.2216 doi:10.7717/peerj.2216 |
| spellingShingle | Yersinia pestis Rodents Screening Microarray Giles, Timothy A. Greenwood, Alex D. Tsangaras, Kyriakos Giles, Tom C. Barrow, Paul A. Hannant, Duncan Abu-Median, Abu-Bakr Yon, Lisa Detection of a Yersinia pestisgene homologue in rodent samples |
| title | Detection of a Yersinia pestisgene homologue in rodent samples |
| title_full | Detection of a Yersinia pestisgene homologue in rodent samples |
| title_fullStr | Detection of a Yersinia pestisgene homologue in rodent samples |
| title_full_unstemmed | Detection of a Yersinia pestisgene homologue in rodent samples |
| title_short | Detection of a Yersinia pestisgene homologue in rodent samples |
| title_sort | detection of a yersinia pestisgene homologue in rodent samples |
| topic | Yersinia pestis Rodents Screening Microarray |
| url | https://eprints.nottingham.ac.uk/38074/ https://eprints.nottingham.ac.uk/38074/ https://eprints.nottingham.ac.uk/38074/ |