The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands
The International Union of Basic and Clinical Pharmacology/British Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY (http://www.guidetopharmacology.org) is a new open access resource providing pharmacological, chemical, genetic, functional and pathophysiological data on the targets of appr...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Published: |
Oxford University Press
2014
|
| Online Access: | https://eprints.nottingham.ac.uk/38017/ |
| _version_ | 1848795580347711488 |
|---|---|
| author | Pawson, Adam J. Sharman, Joanna L. Benson, Helen E. Faccenda, Elena Alexander, Stephen P.H. Buneman, O. Peter Davenport, Anthony P. McGrath, John C. Peters, John A. Southan, Christopher Spedding, Michael Yu, Wenyuan Harmar, Anthony J. |
| author_facet | Pawson, Adam J. Sharman, Joanna L. Benson, Helen E. Faccenda, Elena Alexander, Stephen P.H. Buneman, O. Peter Davenport, Anthony P. McGrath, John C. Peters, John A. Southan, Christopher Spedding, Michael Yu, Wenyuan Harmar, Anthony J. |
| author_sort | Pawson, Adam J. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | The International Union of Basic and Clinical Pharmacology/British Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY (http://www.guidetopharmacology.org) is a new open access resource providing pharmacological, chemical, genetic, functional and pathophysiological data on the targets of approved and experimental drugs. Created under the auspices of the IUPHAR and the BPS, the portal provides concise, peer-reviewed overviews of the key properties of a wide range of established and potential drug targets, with in-depth information for a subset of important targets. The resource is the result of curation and integration of data from the IUPHAR Database (IUPHAR-DB) and the published BPS 'Guide to Receptors and Channels' (GRAC) compendium. The data are derived from a global network of expert contributors, and the information is extensively linked to relevant databases, including ChEMBL, DrugBank, Ensembl, PubChem, UniProt and PubMed. Each of the approximately 6000 small molecule and peptide ligands is annotated with manually curated 2D chemical structures or amino acid sequences, nomenclature and database links. Future expansion of the resource will complete the coverage of all the targets of currently approved drugs and future candidate targets, alongside educational resources to guide scientists and students in pharmacological principles and techniques |
| first_indexed | 2025-11-14T19:34:21Z |
| format | Article |
| id | nottingham-38017 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:34:21Z |
| publishDate | 2014 |
| publisher | Oxford University Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-380172020-05-04T16:40:21Z https://eprints.nottingham.ac.uk/38017/ The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands Pawson, Adam J. Sharman, Joanna L. Benson, Helen E. Faccenda, Elena Alexander, Stephen P.H. Buneman, O. Peter Davenport, Anthony P. McGrath, John C. Peters, John A. Southan, Christopher Spedding, Michael Yu, Wenyuan Harmar, Anthony J. The International Union of Basic and Clinical Pharmacology/British Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY (http://www.guidetopharmacology.org) is a new open access resource providing pharmacological, chemical, genetic, functional and pathophysiological data on the targets of approved and experimental drugs. Created under the auspices of the IUPHAR and the BPS, the portal provides concise, peer-reviewed overviews of the key properties of a wide range of established and potential drug targets, with in-depth information for a subset of important targets. The resource is the result of curation and integration of data from the IUPHAR Database (IUPHAR-DB) and the published BPS 'Guide to Receptors and Channels' (GRAC) compendium. The data are derived from a global network of expert contributors, and the information is extensively linked to relevant databases, including ChEMBL, DrugBank, Ensembl, PubChem, UniProt and PubMed. Each of the approximately 6000 small molecule and peptide ligands is annotated with manually curated 2D chemical structures or amino acid sequences, nomenclature and database links. Future expansion of the resource will complete the coverage of all the targets of currently approved drugs and future candidate targets, alongside educational resources to guide scientists and students in pharmacological principles and techniques Oxford University Press 2014-01-01 Article PeerReviewed Pawson, Adam J., Sharman, Joanna L., Benson, Helen E., Faccenda, Elena, Alexander, Stephen P.H., Buneman, O. Peter, Davenport, Anthony P., McGrath, John C., Peters, John A., Southan, Christopher, Spedding, Michael, Yu, Wenyuan and Harmar, Anthony J. (2014) The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucleic Acids Research, 42 (D1). D1098-D1106. ISSN 1362-4962 http://nar.oxfordjournals.org/content/42/D1/D1098.short doi:10.1093/nar/gkt1143 doi:10.1093/nar/gkt1143 |
| spellingShingle | Pawson, Adam J. Sharman, Joanna L. Benson, Helen E. Faccenda, Elena Alexander, Stephen P.H. Buneman, O. Peter Davenport, Anthony P. McGrath, John C. Peters, John A. Southan, Christopher Spedding, Michael Yu, Wenyuan Harmar, Anthony J. The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands |
| title | The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands |
| title_full | The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands |
| title_fullStr | The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands |
| title_full_unstemmed | The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands |
| title_short | The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands |
| title_sort | iuphar/bps guide to pharmacology: an expert-driven knowledgebase of drug targets and their ligands |
| url | https://eprints.nottingham.ac.uk/38017/ https://eprints.nottingham.ac.uk/38017/ https://eprints.nottingham.ac.uk/38017/ |