Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial
Background: Globally, most strokes occur in low- and middle-income countries, such as India, with many affected people having no or limited access to rehabilitation services. Western models of stroke rehabilitation are often unaffordable in many populations but evidence from systematic reviews of st...
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| Format: | Article |
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BioMed Central
2016
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| Online Access: | https://eprints.nottingham.ac.uk/38009/ |
| _version_ | 1848795578961494016 |
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| author | Alim, Mohammed Lindley, Richard Felix, Cynthia Gandhi, Dorcas Beulah Chandramathy Verma, Shweta Jain Tugnawat, Deepak Kumar Syrigapu, Anuradha Anderson, Craig Stuart Ramamurthy, Ramaprabhu Krishnappa Langhorne, Peter Murthy, Gudlavalleti Venkata Satyanarayana Shamanna, Bindiganavale Ramaswamy Hackett, Maree Lisa Maulik, Pallab Kumar Harvey, Lisa Anne Jan, Stephen Liu, Hueiming Walker, Marion Forster, Anne Pandian, Jeyaraj Durai |
| author_facet | Alim, Mohammed Lindley, Richard Felix, Cynthia Gandhi, Dorcas Beulah Chandramathy Verma, Shweta Jain Tugnawat, Deepak Kumar Syrigapu, Anuradha Anderson, Craig Stuart Ramamurthy, Ramaprabhu Krishnappa Langhorne, Peter Murthy, Gudlavalleti Venkata Satyanarayana Shamanna, Bindiganavale Ramaswamy Hackett, Maree Lisa Maulik, Pallab Kumar Harvey, Lisa Anne Jan, Stephen Liu, Hueiming Walker, Marion Forster, Anne Pandian, Jeyaraj Durai |
| author_sort | Alim, Mohammed |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Background: Globally, most strokes occur in low- and middle-income countries, such as India, with many affected people having no or limited access to rehabilitation services. Western models of stroke rehabilitation are often unaffordable in many populations but evidence from systematic reviews of stroke unit care and early supported discharge rehabilitation trials suggest that some components might form the basis of affordable interventions in low-resource settings. We describe the background, history and design of the ATTEND trial, a complex intervention centred on family-led stroke rehabilitation in India.
Methods/design: The ATTEND trial aims to test the hypothesis that a family-led caregiver-delivered home-based rehabilitation intervention, designed for the Indian context, will reduce the composite poor outcome of death or dependency at 6 months after stroke, in a multicentre, individually randomized controlled trial with blinded outcome assessment, involving 1200 patients across 14 hospital sites in India.
Discussion: The ATTEND trial is testing the effectiveness of a low-cost rehabilitation intervention that could be widely generalizable to other low- and middle-income countries. |
| first_indexed | 2025-11-14T19:34:19Z |
| format | Article |
| id | nottingham-38009 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:34:19Z |
| publishDate | 2016 |
| publisher | BioMed Central |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-380092020-05-04T17:33:00Z https://eprints.nottingham.ac.uk/38009/ Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial Alim, Mohammed Lindley, Richard Felix, Cynthia Gandhi, Dorcas Beulah Chandramathy Verma, Shweta Jain Tugnawat, Deepak Kumar Syrigapu, Anuradha Anderson, Craig Stuart Ramamurthy, Ramaprabhu Krishnappa Langhorne, Peter Murthy, Gudlavalleti Venkata Satyanarayana Shamanna, Bindiganavale Ramaswamy Hackett, Maree Lisa Maulik, Pallab Kumar Harvey, Lisa Anne Jan, Stephen Liu, Hueiming Walker, Marion Forster, Anne Pandian, Jeyaraj Durai Background: Globally, most strokes occur in low- and middle-income countries, such as India, with many affected people having no or limited access to rehabilitation services. Western models of stroke rehabilitation are often unaffordable in many populations but evidence from systematic reviews of stroke unit care and early supported discharge rehabilitation trials suggest that some components might form the basis of affordable interventions in low-resource settings. We describe the background, history and design of the ATTEND trial, a complex intervention centred on family-led stroke rehabilitation in India. Methods/design: The ATTEND trial aims to test the hypothesis that a family-led caregiver-delivered home-based rehabilitation intervention, designed for the Indian context, will reduce the composite poor outcome of death or dependency at 6 months after stroke, in a multicentre, individually randomized controlled trial with blinded outcome assessment, involving 1200 patients across 14 hospital sites in India. Discussion: The ATTEND trial is testing the effectiveness of a low-cost rehabilitation intervention that could be widely generalizable to other low- and middle-income countries. BioMed Central 2016-01-07 Article PeerReviewed Alim, Mohammed, Lindley, Richard, Felix, Cynthia, Gandhi, Dorcas Beulah Chandramathy, Verma, Shweta Jain, Tugnawat, Deepak Kumar, Syrigapu, Anuradha, Anderson, Craig Stuart, Ramamurthy, Ramaprabhu Krishnappa, Langhorne, Peter, Murthy, Gudlavalleti Venkata Satyanarayana, Shamanna, Bindiganavale Ramaswamy, Hackett, Maree Lisa, Maulik, Pallab Kumar, Harvey, Lisa Anne, Jan, Stephen, Liu, Hueiming, Walker, Marion, Forster, Anne and Pandian, Jeyaraj Durai (2016) Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial. Trials, 17 (13). ISSN 1745-6215 Caregivers Costs Disability Rehabilitation Stroke http://trialsjournal.biomedcentral.com/articles/10.1186/s13063-015-1129-8 doi:10.1186/s13063-015-1129-8 doi:10.1186/s13063-015-1129-8 |
| spellingShingle | Caregivers Costs Disability Rehabilitation Stroke Alim, Mohammed Lindley, Richard Felix, Cynthia Gandhi, Dorcas Beulah Chandramathy Verma, Shweta Jain Tugnawat, Deepak Kumar Syrigapu, Anuradha Anderson, Craig Stuart Ramamurthy, Ramaprabhu Krishnappa Langhorne, Peter Murthy, Gudlavalleti Venkata Satyanarayana Shamanna, Bindiganavale Ramaswamy Hackett, Maree Lisa Maulik, Pallab Kumar Harvey, Lisa Anne Jan, Stephen Liu, Hueiming Walker, Marion Forster, Anne Pandian, Jeyaraj Durai Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial |
| title | Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial |
| title_full | Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial |
| title_fullStr | Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial |
| title_full_unstemmed | Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial |
| title_short | Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial |
| title_sort | family-led rehabilitation after stroke in india: the attend trial, study protocol for a randomized controlled trial |
| topic | Caregivers Costs Disability Rehabilitation Stroke |
| url | https://eprints.nottingham.ac.uk/38009/ https://eprints.nottingham.ac.uk/38009/ https://eprints.nottingham.ac.uk/38009/ |